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Liver cirrhosis leads to poorer survival in patients with end-stage renal disease
BACKGROUND/AIMS: Liver cirrhosis (LC) is an important problem in patients withend-stage renal disease (ESRD). Few studies have investigated the inf luence ofLC on mortality in patients with ESRD. This study investigated the associationbetween LC and mortality among patients with ESRD and compare mor...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Association of Internal Medicine
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939491/ https://www.ncbi.nlm.nih.gov/pubmed/27017394 http://dx.doi.org/10.3904/kjim.2014.328 |
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author | Kim, Ae Jin Lim, Hye Jin Ro, Han Jung, Ji Yong Lee, Hyun Hee Chung, Wookyung Chang, Jae Hyun |
author_facet | Kim, Ae Jin Lim, Hye Jin Ro, Han Jung, Ji Yong Lee, Hyun Hee Chung, Wookyung Chang, Jae Hyun |
author_sort | Kim, Ae Jin |
collection | PubMed |
description | BACKGROUND/AIMS: Liver cirrhosis (LC) is an important problem in patients withend-stage renal disease (ESRD). Few studies have investigated the inf luence ofLC on mortality in patients with ESRD. This study investigated the associationbetween LC and mortality among patients with ESRD and compare mortality betweentwo dialysis modalities. METHODS: Adult patients (≥ 18 years of age) starting dialysis for ESRD were enrolledin the present study from 2000 to 2011. We analyzed 1,069 patients withESRD; of these, 742 patients were undergoing hemodialysis (HD) and 327 patientswere undergoing peritoneal dialysis (PD). RESULTS: The prevalence of LC was 44 of 1,069 patients (4.1%). The cumulative 1-,3-, and 5-year survival rates of noncirrhotic patients were 93%, 83%, and 73%, respectively,whereas the equivalent survival rates of cirrhotic patients were 90%,68%, and 48%, respectively (p = 0.011). After adjustment, LC was an independentrisk factor for death in patients with ESRD. No difference in mortality associatedwith LC was found between the HD and PD subgroups. CONCLUSIONS: Of the patients with ESRD, cirrhotic patients had poorer survivalthan noncirrhotic patients. Among patients with ESRD and LC, survival of patientsundergoing PD may be comparable with that of patients undergoing HD. |
format | Online Article Text |
id | pubmed-4939491 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | The Korean Association of Internal Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-49394912016-07-11 Liver cirrhosis leads to poorer survival in patients with end-stage renal disease Kim, Ae Jin Lim, Hye Jin Ro, Han Jung, Ji Yong Lee, Hyun Hee Chung, Wookyung Chang, Jae Hyun Korean J Intern Med Original Article BACKGROUND/AIMS: Liver cirrhosis (LC) is an important problem in patients withend-stage renal disease (ESRD). Few studies have investigated the inf luence ofLC on mortality in patients with ESRD. This study investigated the associationbetween LC and mortality among patients with ESRD and compare mortality betweentwo dialysis modalities. METHODS: Adult patients (≥ 18 years of age) starting dialysis for ESRD were enrolledin the present study from 2000 to 2011. We analyzed 1,069 patients withESRD; of these, 742 patients were undergoing hemodialysis (HD) and 327 patientswere undergoing peritoneal dialysis (PD). RESULTS: The prevalence of LC was 44 of 1,069 patients (4.1%). The cumulative 1-,3-, and 5-year survival rates of noncirrhotic patients were 93%, 83%, and 73%, respectively,whereas the equivalent survival rates of cirrhotic patients were 90%,68%, and 48%, respectively (p = 0.011). After adjustment, LC was an independentrisk factor for death in patients with ESRD. No difference in mortality associatedwith LC was found between the HD and PD subgroups. CONCLUSIONS: Of the patients with ESRD, cirrhotic patients had poorer survivalthan noncirrhotic patients. Among patients with ESRD and LC, survival of patientsundergoing PD may be comparable with that of patients undergoing HD. The Korean Association of Internal Medicine 2016-07 2016-03-26 /pmc/articles/PMC4939491/ /pubmed/27017394 http://dx.doi.org/10.3904/kjim.2014.328 Text en Copyright © 2016 The Korean Association of Internal Medicine This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Kim, Ae Jin Lim, Hye Jin Ro, Han Jung, Ji Yong Lee, Hyun Hee Chung, Wookyung Chang, Jae Hyun Liver cirrhosis leads to poorer survival in patients with end-stage renal disease |
title | Liver cirrhosis leads to poorer survival in patients with end-stage renal disease |
title_full | Liver cirrhosis leads to poorer survival in patients with end-stage renal disease |
title_fullStr | Liver cirrhosis leads to poorer survival in patients with end-stage renal disease |
title_full_unstemmed | Liver cirrhosis leads to poorer survival in patients with end-stage renal disease |
title_short | Liver cirrhosis leads to poorer survival in patients with end-stage renal disease |
title_sort | liver cirrhosis leads to poorer survival in patients with end-stage renal disease |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939491/ https://www.ncbi.nlm.nih.gov/pubmed/27017394 http://dx.doi.org/10.3904/kjim.2014.328 |
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