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Mechanism for insulin-like peptide 5 distinguishing the homologous relaxin family peptide receptor 3 and 4

The relaxin family peptides play a variety of biological functions by activating four G protein-coupled receptors, RXFP1–4. Among them, insulin-like peptide 5 (INSL5) and relaxin-3 share the highest sequence homology, but they have distinct receptor preference: INSL5 can activate RXFP4 only, while r...

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Detalles Bibliográficos
Autores principales:	Hu, Meng-Jun, Shao, Xiao-Xia, Wang, Jia-Hui, Wei, Dian, Guo, Yu-Qi, Liu, Ya-Li, Xu, Zeng-Guang, Guo, Zhan-Yun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939597/ https://www.ncbi.nlm.nih.gov/pubmed/27404393 http://dx.doi.org/10.1038/srep29648

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