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Intercellular Adhesion-Dependent Cell Survival and ROCK-Regulated Actomyosin-Driven Forces Mediate Self-Formation of a Retinal Organoid
In this study we dissected retinal organoid morphogenesis in human embryonic stem cell (hESC)-derived cultures and established a convenient method for isolating large quantities of retinal organoids for modeling human retinal development and disease. Epithelialized cysts were generated via floating...
Autores principales: | Lowe, Albert, Harris, Raven, Bhansali, Punita, Cvekl, Ales, Liu, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939656/ https://www.ncbi.nlm.nih.gov/pubmed/27132890 http://dx.doi.org/10.1016/j.stemcr.2016.03.011 |
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