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Intercellular Adhesion-Dependent Cell Survival and ROCK-Regulated Actomyosin-Driven Forces Mediate Self-Formation of a Retinal Organoid

In this study we dissected retinal organoid morphogenesis in human embryonic stem cell (hESC)-derived cultures and established a convenient method for isolating large quantities of retinal organoids for modeling human retinal development and disease. Epithelialized cysts were generated via floating...

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Detalles Bibliográficos
Autores principales: Lowe, Albert, Harris, Raven, Bhansali, Punita, Cvekl, Ales, Liu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939656/
https://www.ncbi.nlm.nih.gov/pubmed/27132890
http://dx.doi.org/10.1016/j.stemcr.2016.03.011

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