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Knockdown of Progesterone Receptor (PGR) in Macaque Granulosa Cells Disrupts Ovulation and Progesterone Production

Adenoviral vectors (vectors) expressing short-hairpin RNAs complementary to macaque nuclear progesterone (P) receptor PGR mRNA (shPGR) or a nontargeting scrambled control (shScram) were used to determine the role PGR plays in ovulation/luteinization in rhesus monkeys. Nonluteinized granulosa cells c...

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Detalles Bibliográficos
Autores principales: Bishop, Cecily V., Hennebold, Jon D., Kahl, Christoph A., Stouffer, Richard L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for the Study of Reproduction, Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939739/
https://www.ncbi.nlm.nih.gov/pubmed/26985003
http://dx.doi.org/10.1095/biolreprod.115.134981