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Quantitative Proteomics Analysis of VEGF-Responsive Endothelial Protein S-Nitrosylation Using Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC) and LC-MS/MS
Adduction of a nitric oxide moiety (NO•) to cysteine(s), termed S-nitrosylation (SNO), is a novel mechanism for NO to regulate protein function directly. However, the endothelial SNO-protein network that is affected by endogenous and exogenous NO is obscure. This study was designed to develop a quan...
Autores principales: | Zhang, Hong-Hai, Lechuga, Thomas J., Chen, Yuezhou, Yang, Yingying, Huang, Lan, Chen, Dong-Bao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for the Study of Reproduction, Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939742/ https://www.ncbi.nlm.nih.gov/pubmed/27075618 http://dx.doi.org/10.1095/biolreprod.116.139337 |
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