Cargando…

Rosmarinic acid ameliorates hyperglycemia and insulin sensitivity in diabetic rats, potentially by modulating the expression of PEPCK and GLUT4

BACKGROUND: Rosmarinic acid (RA) is a natural substance that may be useful for treating diabetes mellitus. The present study investigated the effects of RA on glucose homeostasis and insulin regulation in rats with streptozocin (STZ)-induced type 1 diabetes or high-fat diet (HFD)-induced type 2 diab...

Descripción completa

Detalles Bibliográficos
Autores principales:	Runtuwene, Joshua, Cheng, Kai-Chun, Asakawa, Akihiro, Amitani, Haruka, Amitani, Marie, Morinaga, Akinori, Takimoto, Yoshiyuki, Kairupan, Bernabas Harold Ralph, Inui, Akio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940010/ https://www.ncbi.nlm.nih.gov/pubmed/27462144 http://dx.doi.org/10.2147/DDDT.S108539

Ejemplares similares

A Role of Ginseng and Its Constituents in the Treatment of Central Nervous System Disorders
por: Rokot, Natasya Trivena, et al.
Publicado: (2016)

Hydrogen–water enhances 5-fluorouracil-induced inhibition of colon cancer
por: Runtuwene, Joshua, et al.
Publicado: (2015)

Allantoin ameliorates chemically-induced pancreatic β-cell damage through activation of the imidazoline I3 receptors
por: Amitani, Marie, et al.
Publicado: (2015)

The role of leptin in the control of insulin-glucose axis
por: Amitani, Marie, et al.
Publicado: (2013)

Stimulation of leptin secretion by insulin
por: Tsai, Minglun, et al.
Publicado: (2012)

The Effectiveness of Cognitive Behavioral Therapy With Mindfulness and an Internet Intervention for Obesity: A Case Series
por: Ogata, Keizaburo, et al.
Publicado: (2018)

Cancer cachexia—pathophysiology and management
por: Suzuki, Hajime, et al.
Publicado: (2013)

The Role of Ghrelin and Ghrelin Signaling in Aging
por: Amitani, Marie, et al.
Publicado: (2017)

One-year intranasal application of growth hormone releasing peptide-2 improves body weight and hypoglycemia in a severely emaciated anorexia nervosa patient
por: Haruta, Izumi, et al.
Publicado: (2015)

The Role of Ghrelin, Salivary Secretions, and Dental Care in Eating Disorders
por: Yagi, Takakazu, et al.
Publicado: (2012)

Rubiscolin-6 activates opioid receptors to enhance glucose uptake in skeletal muscle
por: Kairupan, Timothy Sean, et al.
Publicado: (2018)

The translational aspect of complementary and alternative medicine for cancer with particular emphasis on Kampo
por: Amitani, Marie, et al.
Publicado: (2015)

The relationship between premorbid intelligence and symptoms of severe anorexia nervosa restricting type
por: Ogata, Keizaburo, et al.
Publicado: (2021)

Hydrogen Improves Glycemic Control in Type1 Diabetic Animal Model by Promoting Glucose Uptake into Skeletal Muscle
por: Amitani, Haruka, et al.
Publicado: (2013)

Correction: Hydrogen Improves Glycemic Control in Type1 Diabetic Animal Model by Promoting Glucose Uptake into Skeletal Muscle
por: Amitani, Haruka, et al.
Publicado: (2013)

Silymarin Induces Insulin Resistance through an Increase of Phosphatase and Tensin Homolog in Wistar Rats
por: Cheng, Kai-Chun, et al.
Publicado: (2014)

Impact of Ninjin’yoeito on frailty and short life in klotho-hypomorphic (kl/kl) mice
por: Amitani, Haruka, et al.
Publicado: (2022)

Rice koji reduced body weight gain, fat accumulation, and blood glucose level in high-fat diet-induced obese mice
por: Yoshizaki, Yumiko, et al.
Publicado: (2014)

Role of Musclin in the Pathogenesis of Hypertension in Rat
por: Li, Ying-Xiao, et al.
Publicado: (2013)

Herbal Medicine Ninjin'yoeito in the Treatment of Sarcopenia and Frailty
por: Uto, Nanami Sameshima, et al.
Publicado: (2018)

Correlation between trait emotional intelligence and prefrontal activation during a verbal fluency task: A functional near-infrared spectroscopy study
por: Fukumoto, Takamasa, et al.
Publicado: (2023)

Anti-ghrelin immunoglobulins modulate ghrelin stability and its orexigenic effect in obese mice and humans
por: Takagi, Kuniko, et al.
Publicado: (2013)

Unpredictable refeeding syndrome with severe hypophosphatemia in borderline personality disorder comorbidity: A case report
por: Hamada, Kazumasa, et al.
Publicado: (2023)

Esophageal achalasia, diagnosed through the repeated manometry, alleviated using benzodiazepine: A case report
por: Nishi, Ryusei, et al.
Publicado: (2022)

PEPCK in cancer cell starvation
por: Leithner, Katharina
Publicado: (2015)

Prognostic value of inflammatory biomarkers in aged patients with oral squamous cell carcinoma
por: Yoshimura, Takuya, et al.
Publicado: (2022)

The Effect of Mindfulness Yoga in Children With School Refusal: A Study Protocol for an Exploratory, Cluster-Randomized, Open, Standard Care-Controlled, Multicenter Clinical Trial
por: Amitani, Marie, et al.
Publicado: (2022)

Increased ghrelin signaling prolongs survival in mouse models of human aging through activation of sirtuin1
por: Fujitsuka, N, et al.
Publicado: (2016)

Application of objective structured clinical examination (OSCE) for the evaluation of Kampo medicine training
por: Amitani, Marie, et al.
Publicado: (2022)

The effect of lavender aroma for anxiety disorder: a study protocol for a multicenter, double-masked, randomized, placebo-controlled clinical trial
por: Amitani, Haruka, et al.
Publicado: (2023)

Rosmarinic acid ameliorates HCl-induced cystitis in rats
por: Kitamura, Naoya, et al.
Publicado: (2023)

Ameliorative Effect of Oxytocin on FBN1 and PEPCK Gene Expression, and Behavioral Patterns in Rats' Obesity-Induced Diabetes
por: Elnagar, Asmaa, et al.
Publicado: (2022)

Long-term correction of type 1 and 2 diabetes by central leptin gene therapy independent of effects on appetite and energy expenditure
por: Nakano, Masako, et al.
Publicado: (2012)

TRIM21 ameliorates hepatic glucose and lipid metabolic disorders in type 2 diabetes mellitus by ubiquitination of PEPCK1 and FASN
por: Zhang, Kaini, et al.
Publicado: (2023)

Kobe Earthquake and Post-Traumatic Stress in School-Aged Children
por: Uemoto, Masaharu, et al.
Publicado: (2011)

Prognostic Role of Preoperative Sarcopenia Evaluation of Cervical Muscles with Long-Term Outcomes of Patients with Oral Squamous Cell Carcinoma
por: Yoshimura, Takuya, et al.
Publicado: (2021)

Red rice koji extract alleviates hyperglycemia by increasing glucose uptake and glucose transporter type 4 levels in skeletal muscle in two diabetic mouse models
por: Yagi, Takakazu, et al.
Publicado: (2020)

Gluconeogenesis and PEPCK are critical components of healthy aging and dietary restriction life extension
por: Onken, Brian, et al.
Publicado: (2020)

Glycosylation defects, offset by PEPCK-M, drive entosis in breast carcinoma cells
por: Hyroššová, Petra, et al.
Publicado: (2022)

Rosmarinic acid ameliorates hypoxia/ischemia induced cognitive deficits and promotes remyelination
por: Li, Man, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_c9am1ruuee5al94i3mckuoh9tm