A Tunable Scaffold of Microtubular Graphite for 3D Cell Growth

[Image: see text] Aerographite (AG) is a novel carbon-based material that exists as a self-supportive 3D network of interconnected hollow microtubules. It can be synthesized in a variety of architectures tailored by the growth conditions. This flexibility in creating structures presents interesting...

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Autores principales: Lamprecht, Constanze, Taale, Mohammadreza, Paulowicz, Ingo, Westerhaus, Hannes, Grabosch, Carsten, Schuchardt, Arnim, Mecklenburg, Matthias, Böttner, Martina, Lucius, Ralph, Schulte, Karl, Adelung, Rainer, Selhuber-Unkel, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940076/
https://www.ncbi.nlm.nih.gov/pubmed/27258400
http://dx.doi.org/10.1021/acsami.6b00778
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author Lamprecht, Constanze
Taale, Mohammadreza
Paulowicz, Ingo
Westerhaus, Hannes
Grabosch, Carsten
Schuchardt, Arnim
Mecklenburg, Matthias
Böttner, Martina
Lucius, Ralph
Schulte, Karl
Adelung, Rainer
Selhuber-Unkel, Christine
author_facet Lamprecht, Constanze
Taale, Mohammadreza
Paulowicz, Ingo
Westerhaus, Hannes
Grabosch, Carsten
Schuchardt, Arnim
Mecklenburg, Matthias
Böttner, Martina
Lucius, Ralph
Schulte, Karl
Adelung, Rainer
Selhuber-Unkel, Christine
author_sort Lamprecht, Constanze
collection PubMed
description [Image: see text] Aerographite (AG) is a novel carbon-based material that exists as a self-supportive 3D network of interconnected hollow microtubules. It can be synthesized in a variety of architectures tailored by the growth conditions. This flexibility in creating structures presents interesting bioengineering possibilities such as the generation of an artificial extracellular matrix. Here we have explored the feasibility and potential of AG as a scaffold for 3D cell growth employing cyclic RGD (cRGD) peptides coupled to poly(ethylene glycol) (PEG) conjugated phospholipids for surface functionalization to promote specific adhesion of fibroblast cells. Successful growth and invasion of the bulk material was followed over a period of 4 days.
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spelling pubmed-49400762016-07-12 A Tunable Scaffold of Microtubular Graphite for 3D Cell Growth Lamprecht, Constanze Taale, Mohammadreza Paulowicz, Ingo Westerhaus, Hannes Grabosch, Carsten Schuchardt, Arnim Mecklenburg, Matthias Böttner, Martina Lucius, Ralph Schulte, Karl Adelung, Rainer Selhuber-Unkel, Christine ACS Appl Mater Interfaces [Image: see text] Aerographite (AG) is a novel carbon-based material that exists as a self-supportive 3D network of interconnected hollow microtubules. It can be synthesized in a variety of architectures tailored by the growth conditions. This flexibility in creating structures presents interesting bioengineering possibilities such as the generation of an artificial extracellular matrix. Here we have explored the feasibility and potential of AG as a scaffold for 3D cell growth employing cyclic RGD (cRGD) peptides coupled to poly(ethylene glycol) (PEG) conjugated phospholipids for surface functionalization to promote specific adhesion of fibroblast cells. Successful growth and invasion of the bulk material was followed over a period of 4 days. American Chemical Society 2016-06-03 2016-06-22 /pmc/articles/PMC4940076/ /pubmed/27258400 http://dx.doi.org/10.1021/acsami.6b00778 Text en Copyright © 2016 American Chemical Society This is an open access article published under a Creative Commons Attribution (CC-BY) License (http://pubs.acs.org/page/policy/authorchoice_ccby_termsofuse.html) , which permits unrestricted use, distribution and reproduction in any medium, provided the author and source are cited.
spellingShingle Lamprecht, Constanze
Taale, Mohammadreza
Paulowicz, Ingo
Westerhaus, Hannes
Grabosch, Carsten
Schuchardt, Arnim
Mecklenburg, Matthias
Böttner, Martina
Lucius, Ralph
Schulte, Karl
Adelung, Rainer
Selhuber-Unkel, Christine
A Tunable Scaffold of Microtubular Graphite for 3D Cell Growth
title A Tunable Scaffold of Microtubular Graphite for 3D Cell Growth
title_full A Tunable Scaffold of Microtubular Graphite for 3D Cell Growth
title_fullStr A Tunable Scaffold of Microtubular Graphite for 3D Cell Growth
title_full_unstemmed A Tunable Scaffold of Microtubular Graphite for 3D Cell Growth
title_short A Tunable Scaffold of Microtubular Graphite for 3D Cell Growth
title_sort a tunable scaffold of microtubular graphite for 3d cell growth
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940076/
https://www.ncbi.nlm.nih.gov/pubmed/27258400
http://dx.doi.org/10.1021/acsami.6b00778
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