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Golgi self-correction generates bioequivalent glycans to preserve cellular homeostasis
Essential biological systems employ self-correcting mechanisms to maintain cellular homeostasis. Mammalian cell function is dynamically regulated by the interaction of cell surface galectins with branched N-glycans. Here we report that N-glycan branching deficiency triggers the Golgi to generate bio...
Autores principales: | Mkhikian, Haik, Mortales, Christie-Lynn, Zhou, Raymond W, Khachikyan, Khachik, Wu, Gang, Haslam, Stuart M, Kavarian, Patil, Dell, Anne, Demetriou, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940165/ https://www.ncbi.nlm.nih.gov/pubmed/27269286 http://dx.doi.org/10.7554/eLife.14814 |
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