Inclusion of Strep-Tag II in design of antigen receptors for T cell immunotherapy

The tactical introduction of Strep-tag II into synthetic antigen receptors provides engineered T cells with a marker for identification and rapid purification, and a functional element for selective antibody coated microbead-driven large-scale expansion. Such receptor designs can be applied to chime...

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Detalles Bibliográficos
Autores principales: Liu, Lingfeng, Sommermeyer, Daniel, Cabanov, Alexandra, Kosasih, Paula, Hill, Tyler, Riddell, Stanley R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940167/
https://www.ncbi.nlm.nih.gov/pubmed/26900664
http://dx.doi.org/10.1038/nbt.3461

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940167/
https://www.ncbi.nlm.nih.gov/pubmed/26900664
http://dx.doi.org/10.1038/nbt.3461

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