Cargando…
Inclusion of Strep-Tag II in design of antigen receptors for T cell immunotherapy
The tactical introduction of Strep-tag II into synthetic antigen receptors provides engineered T cells with a marker for identification and rapid purification, and a functional element for selective antibody coated microbead-driven large-scale expansion. Such receptor designs can be applied to chime...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940167/ https://www.ncbi.nlm.nih.gov/pubmed/26900664 http://dx.doi.org/10.1038/nbt.3461 |