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Knock-in Luciferase Reporter Mice for In Vivo Monitoring of CREB Activity
The cAMP response element binding protein (CREB) is induced during fasting in the liver, where it stimulates transcription of rate-limiting gluconeogenic genes to maintain metabolic homeostasis. Adenoviral and transgenic CREB reporters have been used to monitor hepatic CREB activity non-invasively u...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940169/ https://www.ncbi.nlm.nih.gov/pubmed/27336479 http://dx.doi.org/10.1371/journal.pone.0158274 |