Addition of hydrochlorothiazide to angiotensin receptor blocker therapy can achieve a lower sodium balance with no acceleration of intrarenal renin angiotensin system in patients with chronic kidney disease

OBJECTIVE: Angiotensin receptor blockers (ARBs) produce a lower sodium (Na) balance, and the natriuretic effect is enhanced under Na deprivation, despite falls in blood pressure (BP) and glomerular filtration rate (GFR). METHODS: The effect of additional hydrochlorothiazide (HCTZ; 12.5 mg/day) to AR...

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Detalles Bibliográficos
Autores principales: Fuwa, Daisuke, Fukuda, Michio, Ogiyama, Yoshiaki, Sato, Ryo, Mizuno, Masashi, Miura, Toshiyuki, Abe-Dohmae, Sumiko, Michikawa, Makoto, Kobori, Hiroyuki, Ohte, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940185/
https://www.ncbi.nlm.nih.gov/pubmed/27283968
http://dx.doi.org/10.1177/1470320316652032

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