Two New Highly Oxygenated Spirostanol Saponins from Paris polyphylla var. stenophylla

ABSTRACT: Phytochemical investigation of the rhizomes of Paris polyphylla var. stenophylla led to the isolation of two new highly oxygenated spirostanol saponins, named paristenosides A (1) and B (2), together with seven known compounds. Their structures were established mainly on the base of NMR sp...

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Detalles Bibliográficos
Autores principales: Jin, Ling-Yu, Lu, Ting-Xiang, Qin, Xu-Jie, Ni, Wei, Yan, Huan, Chen, Yu, Liu, Hui, He, Hong-Ping, Liu, Hai-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940253/
https://www.ncbi.nlm.nih.gov/pubmed/27255683
http://dx.doi.org/10.1007/s13659-016-0102-x
Descripción
Sumario:ABSTRACT: Phytochemical investigation of the rhizomes of Paris polyphylla var. stenophylla led to the isolation of two new highly oxygenated spirostanol saponins, named paristenosides A (1) and B (2), together with seven known compounds. Their structures were established mainly on the base of NMR spectroscopic techniques and mass spectrometry, as well as chemical methods. In addition, the cytotoxicity of the two new saponins was tested. GRAPHICAL ABSTRACT: Two new highly oxygenated spirostanol saponins, paristenosides A (1) and B (2), were isolated from the rhizomes of Paris polyphylla var. stenophylla. Their structures were established mainly based on NMR spectroscopic techniques and mass spectrometry, as well as chemical methods. [Image: see text] ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s13659-016-0102-x) contains supplementary material, which is available to authorized users.

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