Two New Highly Oxygenated Spirostanol Saponins from Paris polyphylla var. stenophylla

ABSTRACT: Phytochemical investigation of the rhizomes of Paris polyphylla var. stenophylla led to the isolation of two new highly oxygenated spirostanol saponins, named paristenosides A (1) and B (2), together with seven known compounds. Their structures were established mainly on the base of NMR sp...

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Autores principales: Jin, Ling-Yu, Lu, Ting-Xiang, Qin, Xu-Jie, Ni, Wei, Yan, Huan, Chen, Yu, Liu, Hui, He, Hong-Ping, Liu, Hai-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940253/
https://www.ncbi.nlm.nih.gov/pubmed/27255683
http://dx.doi.org/10.1007/s13659-016-0102-x
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author Jin, Ling-Yu
Lu, Ting-Xiang
Qin, Xu-Jie
Ni, Wei
Yan, Huan
Chen, Yu
Liu, Hui
He, Hong-Ping
Liu, Hai-Yang
author_facet Jin, Ling-Yu
Lu, Ting-Xiang
Qin, Xu-Jie
Ni, Wei
Yan, Huan
Chen, Yu
Liu, Hui
He, Hong-Ping
Liu, Hai-Yang
author_sort Jin, Ling-Yu
collection PubMed
description ABSTRACT: Phytochemical investigation of the rhizomes of Paris polyphylla var. stenophylla led to the isolation of two new highly oxygenated spirostanol saponins, named paristenosides A (1) and B (2), together with seven known compounds. Their structures were established mainly on the base of NMR spectroscopic techniques and mass spectrometry, as well as chemical methods. In addition, the cytotoxicity of the two new saponins was tested. GRAPHICAL ABSTRACT: Two new highly oxygenated spirostanol saponins, paristenosides A (1) and B (2), were isolated from the rhizomes of Paris polyphylla var. stenophylla. Their structures were established mainly based on NMR spectroscopic techniques and mass spectrometry, as well as chemical methods. [Image: see text] ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s13659-016-0102-x) contains supplementary material, which is available to authorized users.
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spelling pubmed-49402532016-07-21 Two New Highly Oxygenated Spirostanol Saponins from Paris polyphylla var. stenophylla Jin, Ling-Yu Lu, Ting-Xiang Qin, Xu-Jie Ni, Wei Yan, Huan Chen, Yu Liu, Hui He, Hong-Ping Liu, Hai-Yang Nat Prod Bioprospect Original Article ABSTRACT: Phytochemical investigation of the rhizomes of Paris polyphylla var. stenophylla led to the isolation of two new highly oxygenated spirostanol saponins, named paristenosides A (1) and B (2), together with seven known compounds. Their structures were established mainly on the base of NMR spectroscopic techniques and mass spectrometry, as well as chemical methods. In addition, the cytotoxicity of the two new saponins was tested. GRAPHICAL ABSTRACT: Two new highly oxygenated spirostanol saponins, paristenosides A (1) and B (2), were isolated from the rhizomes of Paris polyphylla var. stenophylla. Their structures were established mainly based on NMR spectroscopic techniques and mass spectrometry, as well as chemical methods. [Image: see text] ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s13659-016-0102-x) contains supplementary material, which is available to authorized users. Springer Berlin Heidelberg 2016-06-02 /pmc/articles/PMC4940253/ /pubmed/27255683 http://dx.doi.org/10.1007/s13659-016-0102-x Text en © The Author(s) 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Original Article
Jin, Ling-Yu
Lu, Ting-Xiang
Qin, Xu-Jie
Ni, Wei
Yan, Huan
Chen, Yu
Liu, Hui
He, Hong-Ping
Liu, Hai-Yang
Two New Highly Oxygenated Spirostanol Saponins from Paris polyphylla var. stenophylla
title Two New Highly Oxygenated Spirostanol Saponins from Paris polyphylla var. stenophylla
title_full Two New Highly Oxygenated Spirostanol Saponins from Paris polyphylla var. stenophylla
title_fullStr Two New Highly Oxygenated Spirostanol Saponins from Paris polyphylla var. stenophylla
title_full_unstemmed Two New Highly Oxygenated Spirostanol Saponins from Paris polyphylla var. stenophylla
title_short Two New Highly Oxygenated Spirostanol Saponins from Paris polyphylla var. stenophylla
title_sort two new highly oxygenated spirostanol saponins from paris polyphylla var. stenophylla
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940253/
https://www.ncbi.nlm.nih.gov/pubmed/27255683
http://dx.doi.org/10.1007/s13659-016-0102-x
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