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Disruption of Vitamin D and Calcium Signaling in Keratinocytes Predisposes to Skin Cancer

1,25 dihydroxyvitamin D (1,25(OH)(2)D), the active metabolite of vitamin D, and calcium regulate epidermal differentiation. 1,25(OH)(2)D exerts its effects through the vitamin D receptor (VDR), a transcription factor in the nuclear hormone receptor family, whereas calcium acts through the calcium se...

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Detalles Bibliográficos
Autores principales:	Bikle, Daniel D., Jiang, Yan, Nguyen, Thai, Oda, Yuko, Tu, Chia-ling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940389/ https://www.ncbi.nlm.nih.gov/pubmed/27462278 http://dx.doi.org/10.3389/fphys.2016.00296

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