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Palindrome-Mediated Translocations in Humans: A New Mechanistic Model for Gross Chromosomal Rearrangements
Palindromic DNA sequences, which can form secondary structures, are widely distributed in the human genome. Although the nature of the secondary structure—single-stranded “hairpin” or double-stranded “cruciform”—has been extensively investigated in vitro, the existence of such unusual non-B DNA in v...
Autores principales: | Inagaki, Hidehito, Kato, Takema, Tsutsumi, Makiko, Ouchi, Yuya, Ohye, Tamae, Kurahashi, Hiroki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940405/ https://www.ncbi.nlm.nih.gov/pubmed/27462347 http://dx.doi.org/10.3389/fgene.2016.00125 |
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