Deletion of the type-1 interferon receptor in APP(SWE)/PS1(ΔE9) mice preserves cognitive function and alters glial phenotype

A neuro-inflammatory response is evident in Alzheimer’s disease (AD), yet the precise mechanisms by which neuro-inflammation influences the progression of Alzheimer’s disease (AD) remain poorly understood. Type-1 interferons (IFNs) are master regulators of innate immunity and have been implicated in...

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Detalles Bibliográficos
Autores principales: Minter, Myles R., Moore, Zachery, Zhang, Moses, Brody, Kate M., Jones, Nigel C., Shultz, Sandy R., Taylor, Juliet M., Crack, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940712/
https://www.ncbi.nlm.nih.gov/pubmed/27400725
http://dx.doi.org/10.1186/s40478-016-0341-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940712/
https://www.ncbi.nlm.nih.gov/pubmed/27400725
http://dx.doi.org/10.1186/s40478-016-0341-4

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