Systemic epigenetic response to recombinant lentiviral vectors independent of proviral integration

BACKGROUND: Lentiviral vectors (LV) are widely used for various gene transfer or gene therapy applications. The effects of LV on target cells are expected to be limited to gene delivery. Yet, human hematopoietic CD34+ cells respond to functional LVs as well as several types of non-integrating LVs by...

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Detalles Bibliográficos
Autores principales: Aranyi, Tamas, Stockholm, Daniel, Yao, Roseline, Poinsignon, Catherine, Wiart, Thibaut, Corre, Guillaume, Touleimat, Nizar, Tost, Jörg, Galy, Anne, Paldi, Andràs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940770/
https://www.ncbi.nlm.nih.gov/pubmed/27408621
http://dx.doi.org/10.1186/s13072-016-0077-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940770/
https://www.ncbi.nlm.nih.gov/pubmed/27408621
http://dx.doi.org/10.1186/s13072-016-0077-1

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