Cargando…

Systemic epigenetic response to recombinant lentiviral vectors independent of proviral integration

BACKGROUND: Lentiviral vectors (LV) are widely used for various gene transfer or gene therapy applications. The effects of LV on target cells are expected to be limited to gene delivery. Yet, human hematopoietic CD34+ cells respond to functional LVs as well as several types of non-integrating LVs by...

Descripción completa

Detalles Bibliográficos
Autores principales:	Aranyi, Tamas, Stockholm, Daniel, Yao, Roseline, Poinsignon, Catherine, Wiart, Thibaut, Corre, Guillaume, Touleimat, Nizar, Tost, Jörg, Galy, Anne, Paldi, Andràs
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940770/ https://www.ncbi.nlm.nih.gov/pubmed/27408621 http://dx.doi.org/10.1186/s13072-016-0077-1

Ejemplares similares

Lentiviral Transduction of CD34(+) Cells Induces Genome-Wide Epigenetic Modifications
por: Yamagata, Yoshiaki, et al.
Publicado: (2012)

Lentiviral standards to determine the sensitivity of assays that quantify lentiviral vector copy numbers and genomic insertion sites in cells
por: Corre, Guillaume, et al.
Publicado: (2022)

Integrated time-lapse and single-cell transcription studies highlight the variable and dynamic nature of human hematopoietic cell fate commitment
por: Moussy, Alice, et al.
Publicado: (2017)

Immunization of Mice with Lentiviral Vectors Targeted to MHC Class II+ Cells Is Due to Preferential Transduction of Dendritic Cells In Vivo
por: Ciré, Séverine, et al.
Publicado: (2014)

Bistable Cell Fate Specification as a Result of Stochastic Fluctuations and Collective Spatial Cell Behaviour
por: Stockholm, Daniel, et al.
Publicado: (2010)

Stochastic Fluctuations and Distributed Control of Gene Expression Impact Cellular Memory
por: Corre, Guillaume, et al.
Publicado: (2014)

Global genome decompaction leads to stochastic activation of gene expression as a first step toward fate commitment in human hematopoietic cells
por: Parmentier, Romuald, et al.
Publicado: (2022)

Production of lentiviral vectors
por: Merten, Otto-Wilhelm, et al.
Publicado: (2016)

Lentiviral Vector Bioprocessing
por: Perry, Christopher, et al.
Publicado: (2021)

WAS Promoter-Driven Lentiviral Vectors Mimic Closely the Lopsided WASP Expression during Megakaryocytic Differentiation
por: Muñoz, Pilar, et al.
Publicado: (2020)

DNA methylation and gene expression patterns in breast cancer progression from in situ carcinoma to invasive carcinoma
por: Fleischer, Thomas, et al.
Publicado: (2013)

Preclinical Development of a Lentiviral Vector for Gene Therapy of X-Linked Severe Combined Immunodeficiency
por: Poletti, Valentina, et al.
Publicado: (2018)

The Inside Out of Lentiviral Vectors
por: Durand, Stéphanie, et al.
Publicado: (2011)

Clinical use of lentiviral vectors
por: Milone, Michael C., et al.
Publicado: (2018)

Special Issue “Lentiviral Vectors”
por: Takeuchi, Yasuhiro
Publicado: (2022)

Serotype-specific Binding Properties and Nanoparticle Characteristics Contribute to the Immunogenicity of rAAV1 Vectors
por: Ferrand, Maxime, et al.
Publicado: (2015)

Epigenetic modifications of HIV proviral LTRs: potential targets for cure
por: Doerfler, W, et al.
Publicado: (2012)

Biosafety Studies of a Clinically Applicable Lentiviral Vector for the Gene Therapy of Artemis-SCID
por: Charrier, Sabine, et al.
Publicado: (2019)

Quantification of lentiviral vector copy numbers in individual hematopoietic colony-forming cells shows vector dose-dependent effects on the frequency and level of transduction
por: Charrier, S, et al.
Publicado: (2011)

Vectofusin-1 Promotes RD114-TR-Pseudotyped Lentiviral Vector Transduction of Human HSPCs and T Lymphocytes
por: Piovan, Claudia, et al.
Publicado: (2017)

Rev-dependent lentiviral expression vector
por: Wu, Yuntao, et al.
Publicado: (2007)

Comparison of lentiviral vector titration methods
por: Geraerts, Martine, et al.
Publicado: (2006)

Construction of shRNA lentiviral vector
por: Song, Hong, et al.
Publicado: (2010)

Reconstructing the immune system with lentiviral vectors
por: Olbrich, Henning, et al.
Publicado: (2017)

The stability of envelope-pseudotyped lentiviral vectors
por: Dautzenberg, Iris J. C., et al.
Publicado: (2020)

An Improved Protocol for the Production of Lentiviral Vectors
por: Brown, Logan Y., et al.
Publicado: (2020)

Lentiviral Vectors for Ocular Gene Therapy
por: Arsenijevic, Yvan, et al.
Publicado: (2022)

Evaluation of diversity indices to estimate clonal dominance in gene therapy studies
por: Corre, Guillaume, et al.
Publicado: (2023)

Differential Regulation of NF-κB-Mediated Proviral and Antiviral Host Gene Expression by Primate Lentiviral Nef and Vpu Proteins
por: Sauter, Daniel, et al.
Publicado: (2015)

Lentiviral Vectors and Cystic Fibrosis Gene Therapy
por: Castellani, Stefano, et al.
Publicado: (2010)

Abrogated cryptic activation of lentiviral transfer vectors
por: Luche, Ralf M., et al.
Publicado: (2012)

Development of lentiviral vectors for gene therapy of arthritis
por: Militello, M, et al.
Publicado: (2001)

Retroviral and Lentiviral Vectors for the Induction of Immunological Tolerance
por: Dufait, Inès, et al.
Publicado: (2012)

Postexit Surface Engineering of Retroviral/Lentiviral Vectors
por: Metzner, Christoph, et al.
Publicado: (2013)

Lentiviral Vector Gene Transfer to Porcine Airways
por: Sinn, Patrick L, et al.
Publicado: (2012)

Lentiviral Vectors for Cancer Immunotherapy and Clinical Applications
por: Liechtenstein, Therese, et al.
Publicado: (2013)

Lentiviral Vectors as Tools for the Study and Treatment of Glioblastoma
por: Del Vecchio, Claudia, et al.
Publicado: (2019)

Design and Potential of Non-Integrating Lentiviral Vectors
por: Shaw, Aaron, et al.
Publicado: (2014)

Cell and Tissue Gene Targeting with Lentiviral Vectors
por: Escors, David, et al.
Publicado: (2012)

Maximizing lentiviral vector gene transfer in the CNS
por: Humbel, Morgane, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_a2g1pf20fbk9206qj8tkgfaf4d