Long noncoding RNAs in DNA methylation: new players stepping into the old game

Long non-coding RNAs (lncRNAs) are being discovered as a novel family of regulators of gene expression at the epigenetic level. Emerging lines of evidence demonstrate that interplays between lncRNAs and DNA methylation machinery are an important layer of epigenetic regulation. Here in this mini-revi...

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Detalles Bibliográficos
Autores principales: Zhao, Yu, Sun, Hao, Wang, Huating
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940868/
https://www.ncbi.nlm.nih.gov/pubmed/27408682
http://dx.doi.org/10.1186/s13578-016-0109-3
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author Zhao, Yu
Sun, Hao
Wang, Huating
author_facet Zhao, Yu
Sun, Hao
Wang, Huating
author_sort Zhao, Yu
collection PubMed
description Long non-coding RNAs (lncRNAs) are being discovered as a novel family of regulators of gene expression at the epigenetic level. Emerging lines of evidence demonstrate that interplays between lncRNAs and DNA methylation machinery are an important layer of epigenetic regulation. Here in this mini-review we summarize the current findings in the field and focus particularly on the interactions mediated through direct physical association between lncRNAs and DNA methyltransferases (DNMTs).
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spelling pubmed-49408682016-07-13 Long noncoding RNAs in DNA methylation: new players stepping into the old game Zhao, Yu Sun, Hao Wang, Huating Cell Biosci Review Long non-coding RNAs (lncRNAs) are being discovered as a novel family of regulators of gene expression at the epigenetic level. Emerging lines of evidence demonstrate that interplays between lncRNAs and DNA methylation machinery are an important layer of epigenetic regulation. Here in this mini-review we summarize the current findings in the field and focus particularly on the interactions mediated through direct physical association between lncRNAs and DNA methyltransferases (DNMTs). BioMed Central 2016-07-11 /pmc/articles/PMC4940868/ /pubmed/27408682 http://dx.doi.org/10.1186/s13578-016-0109-3 Text en © The Author(s) 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Zhao, Yu
Sun, Hao
Wang, Huating
Long noncoding RNAs in DNA methylation: new players stepping into the old game
title Long noncoding RNAs in DNA methylation: new players stepping into the old game
title_full Long noncoding RNAs in DNA methylation: new players stepping into the old game
title_fullStr Long noncoding RNAs in DNA methylation: new players stepping into the old game
title_full_unstemmed Long noncoding RNAs in DNA methylation: new players stepping into the old game
title_short Long noncoding RNAs in DNA methylation: new players stepping into the old game
title_sort long noncoding rnas in dna methylation: new players stepping into the old game
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940868/
https://www.ncbi.nlm.nih.gov/pubmed/27408682
http://dx.doi.org/10.1186/s13578-016-0109-3
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