From animal models to human disease: a genetic approach for personalized medicine in ALS

Amyotrophic Lateral Sclerosis (ALS) is the most frequent motor neuron disease in adults. Classical ALS is characterized by the death of upper and lower motor neurons leading to progressive paralysis. Approximately 10 % of ALS patients have familial form of the disease. Numerous different gene mutati...

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Detalles Bibliográficos
Autores principales: Picher-Martel, Vincent, Valdmanis, Paul N., Gould, Peter V., Julien, Jean-Pierre, Dupré, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940869/
https://www.ncbi.nlm.nih.gov/pubmed/27400686
http://dx.doi.org/10.1186/s40478-016-0340-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940869/
https://www.ncbi.nlm.nih.gov/pubmed/27400686
http://dx.doi.org/10.1186/s40478-016-0340-5

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