Cargando…

LRP1 expression in microglia is protective during CNS autoimmunity

Multiple sclerosis is a devastating neurological disorder characterized by the autoimmune destruction of the central nervous system myelin. While T cells are known orchestrators of the immune response leading to MS pathology, the precise contribution of CNS resident and peripheral infiltrating myelo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chuang, Tzu-Ying, Guo, Yong, Seki, Scott M., Rosen, Abagail M., Johanson, David M., Mandell, James W., Lucchinetti, Claudia F., Gaultier, Alban
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940960/ https://www.ncbi.nlm.nih.gov/pubmed/27400748 http://dx.doi.org/10.1186/s40478-016-0343-2

Ejemplares similares

Role of Microglia in CNS Autoimmunity
por: Goldmann, Tobias, et al.
Publicado: (2013)

Neuronal integrity and complement control synaptic material clearance by microglia after CNS injury
por: Norris, Geoffrey T., et al.
Publicado: (2018)

The Role of Microglia and Macrophages in CNS Homeostasis, Autoimmunity, and Cancer
por: Yin, Jie, et al.
Publicado: (2017)

Experimental autoimmune encephalomyelitis is associated with changes of the microbiota composition in the gastrointestinal tract
por: Johanson, David M., et al.
Publicado: (2020)

Exploring Non-Metabolic Functions of Glycolytic Enzymes in Immunity
por: Seki, Scott M., et al.
Publicado: (2017)

IFNβ secreted by microglia mediates clearance of myelin debris in CNS autoimmunity
por: Kocur, Magdalena, et al.
Publicado: (2015)

The Diverse Roles of Microglia in the Neurodegenerative Aspects of Central Nervous System (CNS) Autoimmunity
por: Thompson, Kaitlyn K., et al.
Publicado: (2017)

Neuron-Specific Vitamin D Signaling Attenuates Microglia Activation and CNS Autoimmunity
por: Lee, Priscilla W., et al.
Publicado: (2020)

p38 MAP Kinase Signaling in Microglia Plays a Sex-Specific Protective Role in CNS Autoimmunity and Regulates Microglial Transcriptional States
por: McGill, Mahalia M., et al.
Publicado: (2021)

Fine-tuning of type I IFN-signaling in microglia — implications for homeostasis, CNS autoimmunity and interferonopathies
por: Goldmann, Tobias, et al.
Publicado: (2016)

Distinctive transcriptomic and epigenomic signatures of bone marrow-derived myeloid cells and microglia in CNS autoimmunity
por: Manouchehri, Navid, et al.
Publicado: (2023)

Presynaptic LRP4 promotes synapse number and function of excitatory CNS neurons
por: Mosca, Timothy J, et al.
Publicado: (2017)

Treg in CNS autoimmune disease
por: Anderton, Stephen M
Publicado: (2012)

Microglia morphophysiological diversity and its implications for the CNS
por: Vidal-Itriago, Andrés, et al.
Publicado: (2022)

Microglia: Agents of the CNS Pro-Inflammatory Response
por: Rodríguez-Gómez, José A., et al.
Publicado: (2020)

IL-10-providing B cells govern pro-inflammatory activity of macrophages and microglia in CNS autoimmunity
por: Geladaris, Anastasia, et al.
Publicado: (2023)

Exploring the VISTA of microglia: immune checkpoints in CNS inflammation
por: Borggrewe, Malte, et al.
Publicado: (2020)

LRP1 plays a major role in the amyloid-β clearance in microglia
por: N’Songo, Aurelie, et al.
Publicado: (2013)

Microglia exit the CNS in spinal root avulsion
por: Green, Lauren A., et al.
Publicado: (2019)

Immune cells and CNS physiology: Microglia and beyond
por: Norris, Geoffrey T., et al.
Publicado: (2019)

Comparative Review of Microglia and Monocytes in CNS Phagocytosis
por: Andoh, Megumi, et al.
Publicado: (2021)

Of primary and secondary CNS autoimmunity
por: Dalmau, Josep
Publicado: (2018)

Determining Immune System Suppression versus CNS Protection for Pharmacological Interventions in Autoimmune Demyelination
por: Evonuk, Kirsten S., et al.
Publicado: (2016)

Deciphering the Footprints of Autoimmunity in CNS Demyelinating Disorders
por: Netravathi, M
Publicado: (2022)

Microglia and CNS Interleukin-1: Beyond Immunological Concepts
por: Liu, Xiaoyu, et al.
Publicado: (2018)

Editorial: Modulation of microglia reactivity and plasticity in CNS injury
por: He, Zhenyan, et al.
Publicado: (2023)

Gut Microbiota to Microglia: Microbiome Influences Neurodevelopment in the CNS
por: Bettag, Jeffery, et al.
Publicado: (2023)

Inhibition of 12/15-lipoxygenase by baicalein induces microglia PPARβ/δ: a potential therapeutic role for CNS autoimmune disease
por: Xu, J, et al.
Publicado: (2013)

Intrinsic TNFR2 signaling in T regulatory cells provides protection in CNS autoimmunity
por: Atretkhany, Kamar-Sulu N., et al.
Publicado: (2018)

LRP5 and LRP6 Are Not Required for Protective Antigen–Mediated Internalization or Lethality of Anthrax Lethal Toxin
por: Young, John J, et al.
Publicado: (2007)

Transplanting Microglia for Treating CNS Injuries and Neurological Diseases and Disorders, and Prospects for Generating Exogenic Microglia
por: Var, Susanna R., et al.
Publicado: (2023)

Impact of Aging in Microglia-Mediated D-Serine Balance in the CNS
por: Beltrán-Castillo, Sebastián, et al.
Publicado: (2018)

Microglia and monocytes in inflammatory CNS disease: integrating phenotype and function
por: Spiteri, Alanna G., et al.
Publicado: (2021)

Mertk-expressing microglia influence oligodendrogenesis and myelin modelling in the CNS
por: Nguyen, Linda T., et al.
Publicado: (2023)

LRP1 regulates peroxisome biogenesis and cholesterol homeostasis in oligodendrocytes and is required for proper CNS myelin development and repair
por: Lin, Jing-Ping, et al.
Publicado: (2017)

Sex bias in CNS autoimmune disease mediated by androgen control of autoimmune regulator
por: Zhu, Meng-Lei, et al.
Publicado: (2016)

Interferon β-Mediated Protective Functions of Microglia in Central Nervous System Autoimmunity
por: Scheu, Stefanie, et al.
Publicado: (2019)

VISTA expression by microglia decreases during inflammation and is differentially regulated in CNS diseases
por: Borggrewe, Malte, et al.
Publicado: (2018)

PEG Minocycline-Liposomes Ameliorate CNS Autoimmune Disease
por: Hu, Wei, et al.
Publicado: (2009)

Origin and Emergence of Microglia in the CNS—An Interesting (Hi)story of an Eccentric Cell
por: Dermitzakis, Iasonas, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_fihrtjpemrlr2tb2c9vc7igcl1