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MCP-1 and eotaxin-1 selectively and negatively associate with memory in MCI and Alzheimer's disease dementia phenotypes

INTRODUCTION: MCP-1 and eotaxin-1 are encoded on chromosome 17 and have been shown to reduce hippocampal neurogenesis in mice. We investigated whether these chemokines selectively associate with memory in individuals with mild cognitive impairment (MCI) and Alzheimer's disease (AD) dementia. ME...

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Detalles Bibliográficos
Autores principales: Bettcher, Brianne M., Fitch, Ryan, Wynn, Matthew J., Lalli, Matthew A., Elofson, Jonathan, Jastrzab, Laura, Mitic, Laura, Miller, Zachary A., Rabinovici, Gil D., Miller, Bruce L., Kao, Aimee W., Kosik, Kenneth S., Kramer, Joel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941041/
https://www.ncbi.nlm.nih.gov/pubmed/27453930
http://dx.doi.org/10.1016/j.dadm.2016.05.004

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