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Associations of sedentary time and patterns of sedentary time accumulation with health-related quality of life in colorectal cancer survivors

Sedentary behavior (sitting/lying at low energy expenditure while awake) is emerging as an important risk factor that may compromise the health-related quality of life (HRQoL) of colorectal cancer (CRC) survivors. We examined associations of sedentary time with HRQoL in CRC survivors, 2–10 years pos...

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Autores principales: van Roekel, Eline H., Winkler, Elisabeth A.H., Bours, Martijn J.L., Lynch, Brigid M., Willems, Paul J.B., Meijer, Kenneth, Kant, IJmert, Beets, Geerard L., Sanduleanu, Silvia, Healy, Genevieve N., Weijenberg, Matty P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941044/
https://www.ncbi.nlm.nih.gov/pubmed/27419042
http://dx.doi.org/10.1016/j.pmedr.2016.06.022
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author van Roekel, Eline H.
Winkler, Elisabeth A.H.
Bours, Martijn J.L.
Lynch, Brigid M.
Willems, Paul J.B.
Meijer, Kenneth
Kant, IJmert
Beets, Geerard L.
Sanduleanu, Silvia
Healy, Genevieve N.
Weijenberg, Matty P.
author_facet van Roekel, Eline H.
Winkler, Elisabeth A.H.
Bours, Martijn J.L.
Lynch, Brigid M.
Willems, Paul J.B.
Meijer, Kenneth
Kant, IJmert
Beets, Geerard L.
Sanduleanu, Silvia
Healy, Genevieve N.
Weijenberg, Matty P.
author_sort van Roekel, Eline H.
collection PubMed
description Sedentary behavior (sitting/lying at low energy expenditure while awake) is emerging as an important risk factor that may compromise the health-related quality of life (HRQoL) of colorectal cancer (CRC) survivors. We examined associations of sedentary time with HRQoL in CRC survivors, 2–10 years post-diagnosis. In a cross-sectional study, stage I–III CRC survivors (n = 145) diagnosed (2002−2010) at Maastricht University Medical Center+, the Netherlands, wore the thigh-mounted MOX activity monitor 24 h/day for seven consecutive days. HRQoL outcomes were assessed by validated questionnaires (EORTC QLQ-C30, WHODAS II, Checklist Individual Strength, and Hospital Anxiety and Depression Scale). Confounder-adjusted linear regression models were used to estimate associations with HRQoL outcomes of MOX-derived total and prolonged sedentary time (in prolonged sedentary bouts ≥ 30 min), and usual sedentary bout duration, corrected for waking wear time. On average, participants spent 10.2 h/day sedentary (SD, 1.6), and 4.5 h/day in prolonged sedentary time (2.3). Mean usual sedentary bout duration was 27.3 min (SD, 16.8). Greater total and prolonged sedentary time, and longer usual sedentary bout duration were associated with significantly (P < 0.05) lower physical functioning, and higher disability and fatigue scores. Greater prolonged sedentary time and longer usual sedentary bout duration also showed significant associations with lower global quality of life and role functioning. Associations with distress and social functioning were non-significant. Sedentary time was cross-sectionally associated with poorer HRQoL outcomes in CRC survivors. Prospective studies are needed to investigate whether sedentary time reduction is a potential target for lifestyle interventions aiming to improve the HRQoL of CRC survivors.
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spelling pubmed-49410442016-07-14 Associations of sedentary time and patterns of sedentary time accumulation with health-related quality of life in colorectal cancer survivors van Roekel, Eline H. Winkler, Elisabeth A.H. Bours, Martijn J.L. Lynch, Brigid M. Willems, Paul J.B. Meijer, Kenneth Kant, IJmert Beets, Geerard L. Sanduleanu, Silvia Healy, Genevieve N. Weijenberg, Matty P. Prev Med Rep Regular Article Sedentary behavior (sitting/lying at low energy expenditure while awake) is emerging as an important risk factor that may compromise the health-related quality of life (HRQoL) of colorectal cancer (CRC) survivors. We examined associations of sedentary time with HRQoL in CRC survivors, 2–10 years post-diagnosis. In a cross-sectional study, stage I–III CRC survivors (n = 145) diagnosed (2002−2010) at Maastricht University Medical Center+, the Netherlands, wore the thigh-mounted MOX activity monitor 24 h/day for seven consecutive days. HRQoL outcomes were assessed by validated questionnaires (EORTC QLQ-C30, WHODAS II, Checklist Individual Strength, and Hospital Anxiety and Depression Scale). Confounder-adjusted linear regression models were used to estimate associations with HRQoL outcomes of MOX-derived total and prolonged sedentary time (in prolonged sedentary bouts ≥ 30 min), and usual sedentary bout duration, corrected for waking wear time. On average, participants spent 10.2 h/day sedentary (SD, 1.6), and 4.5 h/day in prolonged sedentary time (2.3). Mean usual sedentary bout duration was 27.3 min (SD, 16.8). Greater total and prolonged sedentary time, and longer usual sedentary bout duration were associated with significantly (P < 0.05) lower physical functioning, and higher disability and fatigue scores. Greater prolonged sedentary time and longer usual sedentary bout duration also showed significant associations with lower global quality of life and role functioning. Associations with distress and social functioning were non-significant. Sedentary time was cross-sectionally associated with poorer HRQoL outcomes in CRC survivors. Prospective studies are needed to investigate whether sedentary time reduction is a potential target for lifestyle interventions aiming to improve the HRQoL of CRC survivors. Elsevier 2016-07-01 /pmc/articles/PMC4941044/ /pubmed/27419042 http://dx.doi.org/10.1016/j.pmedr.2016.06.022 Text en © 2016 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Regular Article
van Roekel, Eline H.
Winkler, Elisabeth A.H.
Bours, Martijn J.L.
Lynch, Brigid M.
Willems, Paul J.B.
Meijer, Kenneth
Kant, IJmert
Beets, Geerard L.
Sanduleanu, Silvia
Healy, Genevieve N.
Weijenberg, Matty P.
Associations of sedentary time and patterns of sedentary time accumulation with health-related quality of life in colorectal cancer survivors
title Associations of sedentary time and patterns of sedentary time accumulation with health-related quality of life in colorectal cancer survivors
title_full Associations of sedentary time and patterns of sedentary time accumulation with health-related quality of life in colorectal cancer survivors
title_fullStr Associations of sedentary time and patterns of sedentary time accumulation with health-related quality of life in colorectal cancer survivors
title_full_unstemmed Associations of sedentary time and patterns of sedentary time accumulation with health-related quality of life in colorectal cancer survivors
title_short Associations of sedentary time and patterns of sedentary time accumulation with health-related quality of life in colorectal cancer survivors
title_sort associations of sedentary time and patterns of sedentary time accumulation with health-related quality of life in colorectal cancer survivors
topic Regular Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941044/
https://www.ncbi.nlm.nih.gov/pubmed/27419042
http://dx.doi.org/10.1016/j.pmedr.2016.06.022
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