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Metformin in severe exacerbations of chronic obstructive pulmonary disease: a randomised controlled trial

BACKGROUND: Severe exacerbations of COPD are commonly associated with hyperglycaemia, which predicts adverse outcomes. Metformin is a well-established anti-hyperglycaemic agent in diabetes mellitus, possibly augmented with anti-inflammatory effects, but its effects in COPD are unknown. We investigat...

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Detalles Bibliográficos
Autores principales: Hitchings, Andrew W, Lai, Dilys, Jones, Paul W, Baker, Emma H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941151/
https://www.ncbi.nlm.nih.gov/pubmed/26917577
http://dx.doi.org/10.1136/thoraxjnl-2015-208035