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Metformin in severe exacerbations of chronic obstructive pulmonary disease: a randomised controlled trial
BACKGROUND: Severe exacerbations of COPD are commonly associated with hyperglycaemia, which predicts adverse outcomes. Metformin is a well-established anti-hyperglycaemic agent in diabetes mellitus, possibly augmented with anti-inflammatory effects, but its effects in COPD are unknown. We investigat...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941151/ https://www.ncbi.nlm.nih.gov/pubmed/26917577 http://dx.doi.org/10.1136/thoraxjnl-2015-208035 |