Cargando…

MICL controls inflammation in rheumatoid arthritis

BACKGROUND: Myeloid inhibitory C-type lectin-like receptor (MICL, Clec12A) is a C-type lectin receptor (CLR) expressed predominantly by myeloid cells. Previous studies have suggested that MICL is involved in controlling inflammation. OBJECTIVE: To determine the role of this CLR in inflammatory patho...

Descripción completa

Detalles Bibliográficos
Autores principales:	Redelinghuys, Pierre, Whitehead, Lauren, Augello, Andrea, Drummond, Rebecca A, Levesque, Jean-Michel, Vautier, Simon, Reid, Delyth M, Kerscher, Bernhard, Taylor, Julie A, Nigrovic, Peter A, Wright, John, Murray, Graeme I, Willment, Janet A, Hocking, Lynne J, Fernandes, Maria J G, De Bari, Cosimo, Mcinnes, Iain B, Brown, Gordon D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2016
Materias:	Basic and Translational Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941174/ https://www.ncbi.nlm.nih.gov/pubmed/26275430 http://dx.doi.org/10.1136/annrheumdis-2014-206644

Ejemplares similares

Characterisation of the murine C-type lectin receptor CLECSF8 (MCL) reveals its expression on cells of the monocyte/neutrophil lineages and an inter-dependence with Mincle, but not Dectin-2
por: Kerscher, Bernhard, et al.
Publicado: (2015)

Autologous tolerogenic dendritic cells for rheumatoid and inflammatory arthritis
por: Bell, G M, et al.
Publicado: (2017)

Preclinical characterisation of the GM-CSF receptor as a therapeutic target in rheumatoid arthritis
por: Greven, D E A, et al.
Publicado: (2015)

Elevated ACKR2 expression is a common feature of inflammatory arthropathies
por: Baldwin, Helen M., et al.
Publicado: (2017)

Generation and characterisation of therapeutic tolerogenic dendritic cells for rheumatoid arthritis
por: Harry, Rachel A, et al.
Publicado: (2010)

Stem-loops direct precise processing of 3′ UTR-derived small RNA MicL
por: Updegrove, Taylor B, et al.
Publicado: (2019)

Signalling through MyD88 drives surface expression of the mycobacterial receptors MCL (Clecsf8, Clec4d) and Mincle (Clec4e) following microbial stimulation
por: Kerscher, Bernhard, et al.
Publicado: (2016)

Monocyte migration to the synovium in rheumatoid arthritis patients treated with adalimumab
por: Herenius, M M J, et al.
Publicado: (2011)

The JAK inhibitor tofacitinib suppresses synovial JAK1-STAT signalling in rheumatoid arthritis
por: Boyle, D L, et al.
Publicado: (2015)

Crystal structure of Porphyromonas gingivalis peptidylarginine deiminase: implications for autoimmunity in rheumatoid arthritis
por: Montgomery, Anna B, et al.
Publicado: (2016)

Synovial CD4+ T-cell-derived GM-CSF supports the differentiation of an inflammatory dendritic cell population in rheumatoid arthritis
por: Reynolds, G, et al.
Publicado: (2016)

Histone deacetylase 3 regulates the inflammatory gene expression programme of rheumatoid arthritis fibroblast-like synoviocytes
por: Angiolilli, Chiara, et al.
Publicado: (2017)

Promotion of macrophage activation by Tie2 in the context of the inflamed synovia of rheumatoid arthritis and psoriatic arthritis patients
por: Kabala, Pawel A, et al.
Publicado: (2020)

Novel gene variants associated with cardiovascular disease in systemic lupus erythematosus and rheumatoid arthritis
por: Leonard, Dag, et al.
Publicado: (2018)

A homeostatic function of CXCR2 signalling in articular cartilage
por: Sherwood, Joanna, et al.
Publicado: (2015)

The prolactin receptor is expressed in rheumatoid arthritis and psoriatic arthritis synovial tissue and contributes to macrophage activation
por: Tang, Man Wai, et al.
Publicado: (2016)

Expression of chemokines CXCL4 and CXCL7 by synovial macrophages defines an early stage of rheumatoid arthritis
por: Yeo, L, et al.
Publicado: (2016)

Heightened immune response to autocitrullinated Porphyromonas gingivalis peptidylarginine deiminase: a potential mechanism for breaching immunologic tolerance in rheumatoid arthritis
por: Quirke, Anne-Marie, et al.
Publicado: (2014)

Obinutuzumab induces superior B-cell cytotoxicity to rituximab in rheumatoid arthritis and systemic lupus erythematosus patient samples
por: Reddy, Venkat, et al.
Publicado: (2017)

Identification of the NF-κB activating protein-like locus as a risk locus for rheumatoid arthritis
por: Xie, Gang, et al.
Publicado: (2013)

Expression of FcRL4 defines a pro-inflammatory, RANKL-producing B cell subset in rheumatoid arthritis
por: Yeo, L, et al.
Publicado: (2015)

Histone deacetylase inhibitors suppress rheumatoid arthritis fibroblast-like synoviocyte and macrophage IL-6 production by accelerating mRNA decay
por: Grabiec, Aleksander M, et al.
Publicado: (2011)

TLR1/2 and 5 induce elevated cytokine levels from rheumatoid arthritis monocytes independent of ACPA or RF autoantibody status
por: Thwaites, Ryan S, et al.
Publicado: (2020)

Identification of a transitional fibroblast function in very early rheumatoid arthritis
por: Filer, Andrew, et al.
Publicado: (2017)

Effect of the oral application of a highly selective MMP-13 inhibitor in three different animal models of rheumatoid arthritis
por: Jüngel, Astrid, et al.
Publicado: (2009)

Association of circulating miR-223 and miR-16 with disease activity in patients with early rheumatoid arthritis
por: Filková, Mária, et al.
Publicado: (2014)

Mode of action of abatacept in rheumatoid arthritis patients having failed tumour necrosis factor blockade: a histological, gene expression and dynamic magnetic resonance imaging pilot study
por: Buch, M H, et al.
Publicado: (2009)

Targeted delivery of cytokine therapy to rheumatoid tissue by a synovial targeting peptide
por: Wythe, Sarah E, et al.
Publicado: (2013)

Chemotaxis of Vδ2 T cells to the joints contributes to the pathogenesis of rheumatoid arthritis
por: Mo, Wen-Xiu, et al.
Publicado: (2017)

Response to baricitinib based on prior biologic use in patients with refractory rheumatoid arthritis
por: Genovese, Mark C, et al.
Publicado: (2018)

Dendritic cell integrin expression patterns regulate inflammation in the rheumatoid arthritis joint
por: Schittenhelm, Leonie, et al.
Publicado: (2020)

Identification of a novel chemokine-dependent molecular mechanism underlying rheumatoid arthritis-associated autoantibody-mediated bone loss
por: Krishnamurthy, Akilan, et al.
Publicado: (2016)

GBMdeconvoluteR accurately infers proportions of neoplastic and immune cell populations from bulk glioblastoma transcriptomics data
por: Ajaib, Shoaib, et al.
Publicado: (2023)

IL-6-driven STAT signalling in circulating CD4+ lymphocytes is a marker for early anticitrullinated peptide antibody-negative rheumatoid arthritis
por: Anderson, Amy E, et al.
Publicado: (2016)

Mycobacterial receptor, Clec4d (CLECSF8, MCL), is coregulated with Mincle and upregulated on mouse myeloid cells following microbial challenge
por: Kerscher, Bernhard, et al.
Publicado: (2015)

Cytokine mRNA profiling identifies B cells as a major source of RANKL in rheumatoid arthritis
por: Yeo, Lorraine, et al.
Publicado: (2011)

Identification of an immunodominant peptide from citrullinated tenascin-C as a major target for autoantibodies in rheumatoid arthritis
por: Schwenzer, Anja, et al.
Publicado: (2016)

Monocyte alterations in rheumatoid arthritis are dominated by preterm release from bone marrow and prominent triggering in the joint
por: Smiljanovic, Biljana, et al.
Publicado: (2018)

Proteinase-activated receptor 2 modulates OA-related pain, cartilage and bone pathology
por: Huesa, Carmen, et al.
Publicado: (2016)

A CD4 T cell gene signature for early rheumatoid arthritis implicates interleukin 6-mediated STAT3 signalling, particularly in anti-citrullinated peptide antibody-negative disease
por: Pratt, Arthur G, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_ggbo4678i0cf9k7haua72qaeoo