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Reprogramming of energy metabolism as a driver of aging

Aging is characterized by progressive loss of cellular function and integrity. It has been thought to be driven by stochastic molecular damage. However, genetic and environmental maneuvers enhancing mitochondrial function or inhibiting glycolysis extend lifespan and promote healthy aging in many spe...

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Detalles Bibliográficos
Autores principales: Feng, Zhaoyang, Hanson, Richard W., Berger, Nathan A., Trubitsyn, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941250/
https://www.ncbi.nlm.nih.gov/pubmed/26919253
http://dx.doi.org/10.18632/oncotarget.7645