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Pre-neoplastic epigenetic disruption of transcriptional enhancers in chronic inflammation
Chronic periodontitis (CP) is a chronic inflammatory disease independently associated with higher incidence of oral cavity squamous cell carcinoma (OSCC). However, the molecular mechanism responsible for this increased incidence is unknown. Here we profiled the DNA methylome of CP patients and healt...
Autores principales: | Planello, Aline C., Singhania, Rajat, Kron, Ken J., Bailey, Swneke D., Roulois, David, Lupien, Mathieu, Line, Sérgio R. Peres, de Souza, Ana Paula, De Carvalho, Daniel D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941276/ https://www.ncbi.nlm.nih.gov/pubmed/26908456 http://dx.doi.org/10.18632/oncotarget.7513 |
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