miR-30e controls DNA damage-induced stress responses by modulating expression of the CDK inhibitor p21(WAF1/CIP1) and caspase-3

MicroRNAs (miRNAs), a class of small non-coding RNAs that usually cause gene silencing by translational repression or degradation of mRNAs, are implicated in DNA damage-induced stress responses. To identify senescence-associated miRNAs, we performed microarray analyses using wild-type and p53-defici...

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Detalles Bibliográficos
Autores principales: Sohn, Dennis, Peters, Dominik, Piekorz, Roland P., Budach, Wilfried, Jänicke, Reiner U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941286/
https://www.ncbi.nlm.nih.gov/pubmed/26895377
http://dx.doi.org/10.18632/oncotarget.7432

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