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Selective killing of gastric cancer cells by a small molecule via targeting TrxR1 and ROS-mediated ER stress activation

The thioredoxin reductase (TrxR) 1 is often overexpressed in numerous cancer cells. Targeting TrxR1 leads to a reduction in tumor progression and metastasis, making the enzyme an attractive target for cancer treatment. Our previous research revealed that the curcumin derivative B19 could induce canc...

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Detalles Bibliográficos
Autores principales:	Chen, Weiqian, Zou, Peng, Zhao, Zhongwei, Weng, Qiaoyou, Chen, Xi, Ying, Shilong, Ye, Qingqing, Wang, Zhe, Ji, Jiansong, Liang, Guang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941337/ https://www.ncbi.nlm.nih.gov/pubmed/26919094 http://dx.doi.org/10.18632/oncotarget.7565

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