APE1-mediated DNA damage repair provides survival advantage for esophageal adenocarcinoma cells in response to acidic bile salts

Chronic Gastroesophageal Reflux Disease (GERD) is the main risk factor for the development of Barrett's esophagus (BE) and its progression to esophageal adenocarcinoma (EAC). Accordingly, EAC cells are subjected to high levels of oxidative stress and subsequent DNA damage. In this study, we inv...

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Detalles Bibliográficos
Autores principales: Hong, Jun, Chen, Zheng, Peng, Dunfa, Zaika, Alexander, Revetta, Frank, Washington, M. Kay, Belkhiri, Abbes, El-Rifai, Wael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941344/
https://www.ncbi.nlm.nih.gov/pubmed/26934647
http://dx.doi.org/10.18632/oncotarget.7696

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941344/
https://www.ncbi.nlm.nih.gov/pubmed/26934647
http://dx.doi.org/10.18632/oncotarget.7696

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