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Areca nut components stimulate ADAM17, IL-1α, PGE2 and 8-isoprostane production in oral keratinocyte: role of reactive oxygen species, EGF and JAK signaling

Betel quid (BQ) chewing is an etiologic factor of oral submucous fibrosis (OSF) and oral cancer. There are 600 million BQ chewers worldwide. The mechanisms for the toxic and inflammatory responses of BQ are unclear. In this study, both areca nut (AN) extract (ANE) and arecoline stimulated epidermal...

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Detalles Bibliográficos
Autores principales:	Chang, Mei-Chi, Chan, Chiu-Po, Chen, Yi-Jane, Hsien, Hsiang-Chi, Chang, Ya-Ching, Yeung, Sin-Yuet, Jeng, Po-Yuan, Cheng, Ru-Hsiu, Hahn, Liang-Jiunn, Jeng, Jiiang-Huei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941357/ https://www.ncbi.nlm.nih.gov/pubmed/26919242 http://dx.doi.org/10.18632/oncotarget.7621

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