Cargando…

ISG15 predicts poor prognosis and promotes cancer stem cell phenotype in nasopharyngeal carcinoma

Interferon-stimulated gene 15 (ISG15), the first identified ubiquitin-like protein, is known for its anti-viral capacity. However, its role in tumorigenesis remains controversial. Here, using RNA-seq profiling analysis, we identified ISG15 as a differentially expressed gene in nasopharyngeal carcino...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Ren-Hui, Du, Yong, Han, Ping, Wang, Hong-Bo, Liang, Fa-Ya, Feng, Guo-Kai, Zhou, Ai-Jun, Cai, Mu-Yan, Zhong, Qian, Zeng, Mu-Sheng, Huang, Xiao-Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941359/ https://www.ncbi.nlm.nih.gov/pubmed/26919245 http://dx.doi.org/10.18632/oncotarget.7626

Ejemplares similares

Epigenetic downregulation of the ISG15–conjugating enzyme UbcH8 impairs lipolysis and correlates with poor prognosis in nasopharyngeal carcinoma
por: Zhou, Xiaoying, et al.
Publicado: (2015)

Protein tyrosine kinase 6 is associated with nasopharyngeal carcinoma poor prognosis and metastasis
por: Liu, Li-na, et al.
Publicado: (2013)

ISG15: It's Complicated
por: Dzimianski, John V., et al.
Publicado: (2019)

Tumor Cell-Secreted ISG15 Promotes Tumor Cell Migration and Immune Suppression by Inducing the Macrophage M2-Like Phenotype
por: Chen, Ren-Hui, et al.
Publicado: (2020)

Antiviral Properties of ISG15
por: Lenschow, Deborah J.
Publicado: (2010)

The Antiviral Activities of ISG15
por: Morales, David J., et al.
Publicado: (2013)

The ISG15 Conjugation System
por: Durfee, Larissa A., et al.
Publicado: (2011)

ISG15 and immune diseases
por: Jeon, Young Joo, et al.
Publicado: (2010)

High expression of Talin-1 is associated with poor prognosis in patients with nasopharyngeal carcinoma
por: Xu, Ya-Fei, et al.
Publicado: (2015)

Screen for ISG15-crossreactive Deubiquitinases
por: Catic, André, et al.
Publicado: (2007)

ISG15 in antiviral immunity and beyond
por: Perng, Yi-Chieh, et al.
Publicado: (2018)

ISG15 and ISGylation in Human Diseases
por: Mirzalieva, Oygul, et al.
Publicado: (2022)

The ISG15 Conjugation System Broadly Targets Newly Synthesized Proteins: Implications for the Antiviral Function of ISG15
por: Durfee, Larissa A., et al.
Publicado: (2010)

Simultaneous capture of ISG15 conjugating and deconjugating enzymes using a semi-synthetic ISG15-Dha probe
por: Li, Chuntong, et al.
Publicado: (2023)

ISG15 Modulates Development of the Erythroid Lineage
por: Maragno, Ana Leticia, et al.
Publicado: (2011)

ISG15 counteracts Listeria monocytogenes infection
por: Radoshevich, Lilliana, et al.
Publicado: (2015)

ISG15 fast-tracks DNA replication
por: Meroni, Alice, et al.
Publicado: (2020)

ISG15 is associated with cervical cancer development
por: Tao, Pingping, et al.
Publicado: (2022)

The Functional Roles of ISG15/ISGylation in Cancer
por: Yuan, Yin, et al.
Publicado: (2023)

Characterization of the induction kinetics and antiviral functions of IRF1, ISG15 and ISG20 in cells infected with gammacoronavirus avian infectious bronchitis virus
por: Liu, Si Ying, et al.
Publicado: (2023)

Inhibition of ISG15 Enhances the Anti-Cancer Effect of Trametinib in Colon Cancer Cells
por: Zhou, Sheng, et al.
Publicado: (2019)

ISG15 deficiency features a complex cellular phenotype that responds to treatment with itaconate and derivatives
por: Waqas, Syed Fakhar‐ul‐Hassnain, et al.
Publicado: (2022)

Antiviral Activity of Innate Immune Protein ISG15
por: Harty, Ronald N., et al.
Publicado: (2009)

ISG15 deficiency restricts HIV-1 infection
por: Jurczyszak, Denise, et al.
Publicado: (2022)

ISG15 driven cellular responses to virus infection
por: Munnur, Deeksha, et al.
Publicado: (2022)

ISG15 deficiency and increased viral resistance in humans but not mice
por: Speer, Scott D., et al.
Publicado: (2016)

The Criteria to Confirm the Role of Epstein-Barr Virus in Nasopharyngeal Carcinoma Initiation
por: Gu, Ai-Di, et al.
Publicado: (2012)

Structure of interferon‐stimulated gene product 15 (ISG15) from the bat species Myotis davidii and the impact of interdomain ISG15 interactions on viral protein engagement
por: Langley, Caroline, et al.
Publicado: (2019)

ISG15 Inhibits IFN-α-Resistant Liver Cancer Cell Growth
por: Wan, Xin-xing, et al.
Publicado: (2013)

Critical weight loss predicts poor prognosis in nasopharyngeal carcinoma
por: Zeng, Qi, et al.
Publicado: (2016)

ISG15 in the tumorigenesis and treatment of cancer: An emerging role in malignancies of the digestive system
por: Zuo, Chaohui, et al.
Publicado: (2016)

ISG15 induces ESRP1 to inhibit lung adenocarcinoma progression
por: Qu, Tongyuan, et al.
Publicado: (2020)

High expression of TACC3 in esophageal squamous cell carcinoma correlates with poor prognosis
por: Huang, Zhi-Liang, et al.
Publicado: (2015)

Upregulation of KLHDC4 Predicts a Poor Prognosis in Human Nasopharyngeal Carcinoma
por: Lian, Yi-Fan, et al.
Publicado: (2016)

Telomere length regulates ISG15 expression in human cells
por: Lou, Zhenjun, et al.
Publicado: (2009)

Consecutive Inhibition of ISG15 Expression and ISGylation by Cytomegalovirus Regulators
por: Kim, Ye Ji, et al.
Publicado: (2016)

Structural basis of the specificity of USP18 toward ISG15
por: Basters, Anja, et al.
Publicado: (2017)

ISG15 as a prognostic biomarker in solitary fibrous tumour
por: Mondaza-Hernandez, Jose L., et al.
Publicado: (2022)

ISG15 Is Required for the Dissemination of Vaccinia Virus Extracellular Virions
por: Bécares, Martina, et al.
Publicado: (2023)

Chromodomain helicase/ATPase DNA binding protein 1-like protein expression predicts poor prognosis in nasopharyngeal carcinoma
por: SU, FA-REN, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_l32084gckfdbkchc7fni3o6j18