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Comparative analysis of tumor spheroid generation techniques for differential in vitro drug toxicity

Multicellular tumor spheroids are powerful in vitro models to perform preclinical chemosensitivity assays. We compare different methodologies to generate tumor spheroids in terms of resultant spheroid morphology, cellular arrangement and chemosensitivity. We used two cancer cell lines (MCF7 and OVCA...

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Detalles Bibliográficos
Autores principales:	Raghavan, Shreya, Mehta, Pooja, Horst, Eric N., Ward, Maria R., Rowley, Katelyn R., Mehta, Geeta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941362/ https://www.ncbi.nlm.nih.gov/pubmed/26918944 http://dx.doi.org/10.18632/oncotarget.7659

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