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Combination of metronomic cyclophosphamide and dietary intervention inhibits neuroblastoma growth in a CD1-nu mouse model
BACKGROUND: MYCN-amplification in high-grade Neuroblastoma (NB) tumors correlates with increased vascularization and therapy resistance. This study combines an anti-angiogenic approach with targeting NB metabolism for treatment. METHODS AND RESULTS: Metronomic cyclophosphamide (MCP) monotherapy sign...
Autores principales: | Morscher, Raphael Johannes, Aminzadeh-Gohari, Sepideh, Hauser-Kronberger, Cornelia, Feichtinger, René Günther, Sperl, Wolfgang, Kofler, Barbara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941371/ https://www.ncbi.nlm.nih.gov/pubmed/26959744 http://dx.doi.org/10.18632/oncotarget.7929 |
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