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Suppression of PPARγ-mediated monoacylglycerol O-acyltransferase 1 expression ameliorates alcoholic hepatic steatosis

Alcohol consumption is one of the major causes of hepatic steatosis, fibrosis, cirrhosis, and superimposed hepatocellular carcinoma. Ethanol metabolism alters the NAD(+)/NADH ratio, thereby suppressing the activity of sirtuin family proteins, which may affect lipid metabolism in liver cells. However...

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Detalles Bibliográficos
Autores principales:	Yu, Jung Hwan, Song, Su Jin, Kim, Ara, Choi, Yoonjeong, Seok, Jo Woon, Kim, Hyo Jung, Lee, Yoo Jeong, Lee, Kwan Sik, Kim, Jae-woo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941543/ https://www.ncbi.nlm.nih.gov/pubmed/27404390 http://dx.doi.org/10.1038/srep29352

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