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Viral Evolution and Cytotoxic T Cell Restricted Selection in Acute Infant HIV-1 Infection

Antiretroviral therapy-naive HIV-1 infected infants experience poor viral containment and rapid disease progression compared to adults. Viral factors (e.g. transmitted cytotoxic T- lymphocyte (CTL) escape mutations) or infant factors (e.g. reduced CTL functional capacity) may explain this observatio...

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Detalles Bibliográficos
Autores principales:	Garcia-Knight, Miguel A., Slyker, Jennifer, Payne, Barbara Lohman, Pond, Sergei L. Kosakovsky, de Silva, Thushan I., Chohan, Bhavna, Khasimwa, Brian, Mbori-Ngacha, Dorothy, John-Stewart, Grace, Rowland-Jones, Sarah L., Esbjörnsson, Joakim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941567/ https://www.ncbi.nlm.nih.gov/pubmed/27403940 http://dx.doi.org/10.1038/srep29536

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