Potent response of QS-21 as a vaccine adjuvant in the skin when delivered with the Nanopatch, resulted in adjuvant dose sparing

Adjuvants play a key role in boosting immunogenicity of vaccines, particularly for subunit protein vaccines. In this study we investigated the induction of antibody response against trivalent influenza subunit protein antigen and a saponin adjuvant, QS-21. Clinical trials of QS-21 have demonstrated...

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Detalles Bibliográficos
Autores principales: Ng, Hwee-Ing, Fernando, Germain J. P., Depelsenaire, Alexandra C. I., Kendall, Mark A. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941647/
https://www.ncbi.nlm.nih.gov/pubmed/27404789
http://dx.doi.org/10.1038/srep29368

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