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Murine matrix metalloproteinase-20 overexpression stimulates cell invasion into the enamel layer via enhanced Wnt signaling

Matrix metalloproteinase-20 (MMP20) is expressed by ameloblasts in developing teeth and MMP20 mutations cause enamel malformation. We established a stably transfected Tet-Off Mmp20-inducible ameloblast-lineage cell line and found that MMP20 expression promoted cell invasion. Previously, we engineere...

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Detalles Bibliográficos
Autores principales: Shin, Masashi, Suzuki, Maiko, Guan, Xiaomu, Smith, Charles E., Bartlett, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941722/
https://www.ncbi.nlm.nih.gov/pubmed/27403713
http://dx.doi.org/10.1038/srep29492

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