Identification of 4-aminoquinoline core for the design of new cholinesterase inhibitors

Inhibition of acetylcholinesterase (AChE) using small molecules is still one of the most successful therapeutic strategies in the treatment of Alzheimer’s disease (AD). Previously we reported compound T5369186 with a core of quinolone as a new cholinesterase inhibitor. In the present study, in order...

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Detalles Bibliográficos
Autores principales: Chen, Yao, Bian, Yaoyao, Sun, Yuan, Kang, Chen, Yu, Sheng, Fu, Tingming, Li, Wei, Pei, Yuqiong, Sun, Haopeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2016
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941764/
https://www.ncbi.nlm.nih.gov/pubmed/27441112
http://dx.doi.org/10.7717/peerj.2140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941764/
https://www.ncbi.nlm.nih.gov/pubmed/27441112
http://dx.doi.org/10.7717/peerj.2140

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