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In-vivo imaging of dendritic pruning in dentate granule cells
We longitudinally imaged the developing dendrites of adult-born mouse dentate granule cells (DGCs) in vivo and found that they underwent over-branching and pruning. Exposure to an enriched environment (EE) and constraining dendritic growth by disrupting Wnt signaling led to increased branch addition...
Autores principales: | Gonçalves, J. Tiago, Bloyd, Cooper W., Shtrahman, Matthew, Johnston, Stephen T., Schafer, Simon T., Parylak, Sarah L., Tran, Thanh, Chang, Tina, Gage, Fred H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941946/ https://www.ncbi.nlm.nih.gov/pubmed/27135217 http://dx.doi.org/10.1038/nn.4301 |
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