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Structure and Function of the Su(H)-Hairless Repressor Complex, the Major Antagonist of Notch Signaling in Drosophila melanogaster

Notch is a conserved signaling pathway that specifies cell fates in metazoans. Receptor-ligand interactions induce changes in gene expression, which is regulated by the transcription factor CBF1/Su(H)/Lag-1 (CSL). CSL interacts with coregulators to repress and activate transcription from Notch targe...

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Detalles Bibliográficos
Autores principales:	Yuan, Zhenyu, Praxenthaler, Heiko, Tabaja, Nassif, Torella, Rubben, Preiss, Anette, Maier, Dieter, Kovall, Rhett A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942083/ https://www.ncbi.nlm.nih.gov/pubmed/27404588 http://dx.doi.org/10.1371/journal.pbio.1002509

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