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Glucocorticoids Alter CRTC-CREB Signaling in Muscle Cells: Impact on PGC-1α Expression and Atrophy Markers

Muscle wasting associated with chronic diseases has been linked to decreased expression of PGC-1α and overexpression of PGC-1α counters muscle loss. CREB, in conjunction with the CREB-regulated transcription coactivator (CRTC2), is a positive modulator of PGC-1α transcription. We previously reported...

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Detalles Bibliográficos
Autores principales:	Rahnert, Jill A., Zheng, Bin, Hudson, Matthew B., Woodworth-Hobbs, Myra E., Price, S. Russ
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942104/ https://www.ncbi.nlm.nih.gov/pubmed/27404111 http://dx.doi.org/10.1371/journal.pone.0159181

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