Cargando…

High Content Screening Analysis to Evaluate the Toxicological Effects of Harmful and Potentially Harmful Constituents (HPHC)

Cigarette smoke (CS) is a major risk factor for cardiovascular and lung diseases. Because CS is a complex aerosol containing more than 7,000 chemicals(1) it is challenging to assess the contributions of individual constituents to its overall toxicity. Toxicological profiles of individual constituent...

Descripción completa

Detalles Bibliográficos
Autores principales:	Marescotti, Diego, Gonzalez Suarez, Ignacio, Acali, Stefano, Johne, Stephanie, Laurent, Alexandra, Frentzel, Stefan, Hoeng, Julia, Peitsch, Manuel C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MyJove Corporation 2016
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942107/ https://www.ncbi.nlm.nih.gov/pubmed/27228213 http://dx.doi.org/10.3791/53987

Ejemplares similares

GladiaTOX: GLobal Assessment of Dose-IndicAtor in TOXicology
por: Belcastro, Vincenzo, et al.
Publicado: (2019)

A framework for in vitro systems toxicology assessment of e-liquids
por: Iskandar, Anita R., et al.
Publicado: (2016)

Systems toxicology assessment of a representative e-liquid formulation using human primary bronchial epithelial cells
por: Marescotti, Diego, et al.
Publicado: (2019)

The Apoe(−/−) mouse model: a suitable model to study cardiovascular and respiratory diseases in the context of cigarette smoke exposure and harm reduction
por: Lo Sasso, Giuseppe, et al.
Publicado: (2016)

Harmful and Potentially Harmful Constituents in the Filler and Smoke of Tobacco-Containing Tobacco Products
por: Cheng, Tianrong, et al.
Publicado: (2022)

Toxicological Assessment of Flavor Ingredients in E-Vapor Products
por: Sciuscio, Davide, et al.
Publicado: (2022)

Reduced Exposure to Harmful and Potentially Harmful Smoke Constituents With the Tobacco Heating System 2.1
por: Lüdicke, Frank, et al.
Publicado: (2017)

Development of an Advanced Multicellular Intestinal Model for Assessing Immunomodulatory Properties of Anti-Inflammatory Compounds
por: Marescotti, Diego, et al.
Publicado: (2021)

Proteomics for systems toxicology
por: Titz, Bjoern, et al.
Publicado: (2014)

The effectiveness of moderating harmful online content
por: Schneider, Philipp J., et al.
Publicado: (2023)

Real-World Evidence of Differences in Biomarkers of Exposure to Select Harmful and Potentially Harmful Constituents and Biomarkers of Potential Harm Between Adult E-Vapor Users and Adult Cigarette Smokers
por: Oliveri, Douglas, et al.
Publicado: (2019)

α-Glucosidase Inhibitory Constituents from Acanthopanax senticosus Harm Leaves
por: Wang, Zhi-Bin, et al.
Publicado: (2012)

Toxicological studies of stem bark extract from Schefflera barteri Harms (Araliaceae)
por: Atsafack, Serge Secco, et al.
Publicado: (2015)

What is the harm in harmful conception? On threshold harms in non-identity cases
por: Williams, Nicola J., et al.
Publicado: (2014)

To Cause Harm and to be Harmed by Others: New Perspectives on Alcohol’s Harms to Others
por: Seid, Abdu K., et al.
Publicado: (2015)

Expanded View of PAHs: Identifying Especially Harmful Constituents of Bituminous Coal Smoke
por: Seltenrich, Nate
Publicado: (2020)

In vitro systems toxicology approach to investigate the effects of repeated cigarette smoke exposure on human buccal and gingival organotypic epithelial tissue cultures
por: Schlage, Walter K., et al.
Publicado: (2014)

Systems Toxicology Approach for Assessing Developmental Neurotoxicity in Larval Zebrafish
por: Li, Roman A., et al.
Publicado: (2021)

Reductions in biomarkers of exposure (BoE) to harmful or potentially harmful constituents (HPHCs) following partial or complete substitution of cigarettes with electronic cigarettes in adult smokers
por: O’Connell, Grant, et al.
Publicado: (2016)

Understanding international perceptions of the severity of harmful content online
por: Jiang, Jialun Aaron, et al.
Publicado: (2021)

Systems toxicology approaches enable mechanistic comparison of spontaneous and cigarette smoke-related lung tumor development in the A/J mouse model
por: Luettich, Karsta, et al.
Publicado: (2014)

Respiratory Effects of Exposure to Aerosol From the Candidate Modified-Risk Tobacco Product THS 2.2 in an 18-Month Systems Toxicology Study With A/J Mice
por: Titz, Bjoern, et al.
Publicado: (2020)

Systems Toxicology: From Basic Research to Risk Assessment
por: Sturla, Shana J., et al.
Publicado: (2014)

Reductions in biomarkers of exposure to selected harmful and potentially harmful constituents following exclusive and partial switching from combustible cigarettes to myblu(™) electronic nicotine delivery systems (ENDS)
por: Morris, Paul, et al.
Publicado: (2021)

Harmful and potentially harmful constituents (HPHCs) in two novel nicotine pouch products in comparison with regular smokeless tobacco products and pharmaceutical nicotine replacement therapy products (NRTs)
por: Back, Susanne, et al.
Publicado: (2023)

Harmful intent /
por: Cook, Robin, 1940-
Publicado: (1990)

Harmful Farming
por: Adler, T
Publicado: (2002)

Harmful intent /
por: Cook, Robin, 1940-
Publicado: (1991)

Harmful Certification?
Publicado: (1956)

The Harm in Kratom
por: Drago, Joshua Z., et al.
Publicado: (2017)

What's the Harm?
por: Dizon, Don S.
Publicado: (2017)

No Harm Done?
por: Crawford, Mike
Publicado: (1999)

Screening for Chronic Kidney Disease: Preventing Harm or Harming the Healthy?
por: Taal, Maarten W.
Publicado: (2012)

Do no harm: no psychological harm from colorectal cancer screening
por: Kirkøen, Benedicte, et al.
Publicado: (2016)

Islamic Jurisprudence on Harm Versus Harm Scenarios in Medical Confidentiality
por: Muhsin, Sayyed Mohamed
Publicado: (2023)

The challenges of responding to misinformation during a pandemic: content moderation and the limitations of the concept of harm
por: Baker, Stephanie Alice, et al.
Publicado: (2020)

When self-harm is about preventing harm: emergency management of obsessive–compulsive disorder and associated self-harm
por: Palombini, Erika, et al.
Publicado: (2021)

Systems toxicology meta-analysis of in vitro assessment studies: biological impact of a candidate modified-risk tobacco product aerosol compared with cigarette smoke on human organotypic cultures of the aerodigestive tract
por: Iskandar, A. R., et al.
Publicado: (2017)

Supporting evidence-based analysis for modified risk tobacco products through a toxicology data-sharing infrastructure
por: Boué, Stéphanie, et al.
Publicado: (2017)

Comparative effects of a candidate modified-risk tobacco product Aerosol and cigarette smoke on human organotypic small airway cultures: a systems toxicology approach
por: Iskandar, Anita R., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_5o8sduvfhl4f4e684m9ebvq2br