Hydrodynamic Radii of Ranibizumab, Aflibercept and Bevacizumab Measured by Time-Resolved Phosphorescence Anisotropy

PURPOSE: To measure the hydrodynamic radii of intravitreal anti-VEGF drugs ranibizumab, aflibercept and bevacizumab with μs time-resolved phosphorescence anisotropy. METHODS: Ruthenium-based dye Ru(bpy)(2)(mcbpy − O − Su − ester)(PF(6))(2), whose lifetime of several hundred nanoseconds is comparable...

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Detalles Bibliográficos
Autores principales: Hirvonen, Liisa M., Fruhwirth, Gilbert O., Srikantha, Nishanthan, Barber, Matthew J., Neffendorf, James E., Suhling, Klaus, Jackson, Timothy L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942501/
https://www.ncbi.nlm.nih.gov/pubmed/27225494
http://dx.doi.org/10.1007/s11095-016-1940-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942501/
https://www.ncbi.nlm.nih.gov/pubmed/27225494
http://dx.doi.org/10.1007/s11095-016-1940-2

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