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Hydrodynamic Radii of Ranibizumab, Aflibercept and Bevacizumab Measured by Time-Resolved Phosphorescence Anisotropy
PURPOSE: To measure the hydrodynamic radii of intravitreal anti-VEGF drugs ranibizumab, aflibercept and bevacizumab with μs time-resolved phosphorescence anisotropy. METHODS: Ruthenium-based dye Ru(bpy)(2)(mcbpy − O − Su − ester)(PF(6))(2), whose lifetime of several hundred nanoseconds is comparable...
Autores principales: | Hirvonen, Liisa M., Fruhwirth, Gilbert O., Srikantha, Nishanthan, Barber, Matthew J., Neffendorf, James E., Suhling, Klaus, Jackson, Timothy L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942501/ https://www.ncbi.nlm.nih.gov/pubmed/27225494 http://dx.doi.org/10.1007/s11095-016-1940-2 |
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