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Homologous recombination-dependent repair of telomeric DSBs in proliferating human cells

Telomeres prevent chromosome ends from being recognized as double-stranded breaks (DSBs). Meanwhile, G/C-rich repetitive telomeric DNA is susceptible to attack by DNA-damaging agents. How cells balance the need to protect DNA ends and the need to repair DNA lesions in telomeres is unknown. Here we s...

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Detalles Bibliográficos
Autores principales:	Mao, Pingsu, Liu, Jingfan, Zhang, Zepeng, Zhang, Hong, Liu, Haiying, Gao, Song, Rong, Yikang S., Zhao, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942568/ https://www.ncbi.nlm.nih.gov/pubmed/27396625 http://dx.doi.org/10.1038/ncomms12154

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