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APOE2 Is Associated with Spatial Navigational Strategies and Increased Gray Matter in the Hippocampus

The Apolipoprotein E (APOE) gene has a strong association with Alzheimer’s disease (AD). The ε4 allele is a well-documented genetic risk factor of AD. In contrast, the ε2 allele of the APOE gene is known to be protective against AD. Much of the focus on the APOE gene has been on the ε4 allele in bot...

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Detalles Bibliográficos
Autores principales: Konishi, Kyoko, Bhat, Venkat, Banner, Harrison, Poirier, Judes, Joober, Ridha, Bohbot, Véronique D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942687/
https://www.ncbi.nlm.nih.gov/pubmed/27468260
http://dx.doi.org/10.3389/fnhum.2016.00349