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Methane limit LPS-induced NF-κB/MAPKs signal in macrophages and suppress immune response in mice by enhancing PI3K/AKT/GSK-3β-mediated IL-10 expression
Inflammatory diseases such as sepsis and autoimmune colitis, characterized by an overwhelming activation of the immune system and the counteracting anti-inflammatory response, remain a major health problem in worldwide. Emerging evidence suggests that methane have a protective effect on many animal...
Autores principales: | Zhang, Xu, Li, Na, Shao, Han, Meng, Yan, Wang, Liping, Wu, Qian, Yao, Ying, Li, Jinbao, Bian, Jinjun, Zhang, Yan, Deng, Xiaoming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942692/ https://www.ncbi.nlm.nih.gov/pubmed/27405597 http://dx.doi.org/10.1038/srep29359 |
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