Cargando…

Methane limit LPS-induced NF-κB/MAPKs signal in macrophages and suppress immune response in mice by enhancing PI3K/AKT/GSK-3β-mediated IL-10 expression

Inflammatory diseases such as sepsis and autoimmune colitis, characterized by an overwhelming activation of the immune system and the counteracting anti-inflammatory response, remain a major health problem in worldwide. Emerging evidence suggests that methane have a protective effect on many animal...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Xu, Li, Na, Shao, Han, Meng, Yan, Wang, Liping, Wu, Qian, Yao, Ying, Li, Jinbao, Bian, Jinjun, Zhang, Yan, Deng, Xiaoming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942692/ https://www.ncbi.nlm.nih.gov/pubmed/27405597 http://dx.doi.org/10.1038/srep29359

Ejemplares similares

MALAT1 promotes platelet activity and thrombus formation through PI3k/Akt/GSK-3β signalling pathway
por: Sun, Yeying, et al.
Publicado: (2022)

Polydatin Prevents Lipopolysaccharide (LPS)-Induced Parkinson's Disease via Regulation of the AKT/GSK3β-Nrf2/NF-κB Signaling Axis
por: Huang, Bingxu, et al.
Publicado: (2018)

Anti-inflammatory effects of Phyllanthus amarus Schum. & Thonn. through inhibition of NF-κB, MAPK, and PI3K-Akt signaling pathways in LPS-induced human macrophages
por: Harikrishnan, Hemavathy, et al.
Publicado: (2018)

Astaxanthin suppresses lipopolysaccharide-induced myocardial injury by regulating MAPK and PI3K/AKT/mTOR/GSK3β signaling
por: Xie, Wen-Jie, et al.
Publicado: (2020)

20-Hydroxy-3-Oxolupan-28-Oic Acid Attenuates Inflammatory Responses by Regulating PI3K–Akt and MAPKs Signaling Pathways in LPS-Stimulated RAW264.7 Macrophages
por: Cao, Yufeng, et al.
Publicado: (2019)

LY3023414 inhibits both osteogenesis and osteoclastogenesis through the PI3K/Akt/GSK3 signalling pathway
por: Chen, Xiaojun, et al.
Publicado: (2021)

Roles of PI3K/AKT/GSK3 Pathway Involved in Psychiatric Illnesses
por: Matsuda, Satoru, et al.
Publicado: (2019)

6-Methylcoumarin Promotes Melanogenesis through the PKA/CREB, MAPK, AKT/PI3K, and GSK3β/β-Catenin Signaling Pathways
por: Kim, Taejin, et al.
Publicado: (2023)

Overstimulation can create health problems due to increases in PI3K/Akt/GSK3 insensitivity and GSK3 activity
por: Liu, Xunxian
Publicado: (2014)

Dexmedetomidine Alleviates LPS-Induced Neuronal Dysfunction by Modulating the AKT/GSK-3β/CRMP-2 Pathway in Hippocampal Neurons
por: Zeng, Wei, et al.
Publicado: (2021)

Phosphorylated GSK-3β protects stress-induced apoptosis of myoblasts via the PI3K/Akt signaling pathway
por: Liu, Meixi, et al.
Publicado: (2020)

Rutaecarpine ameliorates osteoarthritis by inhibiting PI3K/AKT/NF-κB and MAPK signalling transduction through integrin αVβ3
por: Wan, Junlai, et al.
Publicado: (2023)

Eupafolin induces apoptosis and autophagy of breast cancer cells through PI3K/AKT, MAPKs and NF-κB signaling pathways
por: Wei, Jiahui, et al.
Publicado: (2021)

The Roles of PI3K/AKT/mTOR and MAPK/ERK Signaling Pathways in Human Pheochromocytomas
por: Du, Juan, et al.
Publicado: (2016)

Different activation of MAPKs and Akt/GSK3β after preload vs. afterload elevation
por: Hartmann, Nico, et al.
Publicado: (2022)

Dietary regulation of PI3K/AKT/GSK-3β pathway in Alzheimer’s disease
por: Kitagishi, Yasuko, et al.
Publicado: (2014)

Role of PI3K/Akt/GSK-3 Pathway in Emesis and Potential New Antiemetics
por: Zhong, W, et al.
Publicado: (2020)

Polydatin inhibits mast cell-mediated allergic inflammation by targeting PI3K/Akt, MAPK, NF-κB and Nrf2/HO-1 pathways
por: Ye, Jing, et al.
Publicado: (2017)

Quercetin Protects against Okadaic Acid-Induced Injury via MAPK and PI3K/Akt/GSK3β Signaling Pathways in HT22 Hippocampal Neurons
por: Jiang, Wei, et al.
Publicado: (2016)

GSK3β inhibition attenuates LPS-induced IL-6 expression in porcine adipocytes
por: Wang, Linjie, et al.
Publicado: (2018)

Pioglitazone Protected against Cardiac Hypertrophy via Inhibiting AKT/GSK3β and MAPK Signaling Pathways
por: Wei, Wen-Ying, et al.
Publicado: (2016)

Phenethylferulate as a natural inhibitor of inflammation in LPS-stimulated RAW 264.7 macrophages: focus on NF-κB, Akt and MAPK signaling pathways
por: Yan, Zhongjie, et al.
Publicado: (2023)

Downregulation of BANCR Promotes Aggressiveness in Papillary Thyroid Cancer via the MAPK and PI3K Pathways
por: Zhang, Jinjun, et al.
Publicado: (2018)

Sulforaphane Ameliorates the Intestinal Injury in Necrotizing Enterocolitis by Regulating the PI3K/Akt/GSK-3β Signaling Pathway
por: Bao, Zhong-Kun, et al.
Publicado: (2022)

The Neuroprotection of Liraglutide Against Ischaemia-induced Apoptosis through the Activation of the PI3K/AKT and MAPK Pathways
por: Zhu, Huili, et al.
Publicado: (2016)

Time-dependent activation of MAPK/Erk1/2 and Akt/GSK3 cascades: modulation by agomelatine
por: Musazzi, Laura, et al.
Publicado: (2014)

Mycobacterial Heparin-binding Hemagglutinin Antigen Activates Inflammatory Responses through PI3-K/Akt, NF-κB, and MAPK Pathways
por: Kim, Ki-Hye, et al.
Publicado: (2011)

Liraglutide Protects Nucleus Pulposus Cells Against High-Glucose Induced Apoptosis by Activating PI3K/Akt/ mTOR/Caspase-3 and PI3K/Akt/GSK3β/Caspase-3 Signaling Pathways
por: Yao, Mingyan, et al.
Publicado: (2021)

Discovery of an evodiamine derivative for PI3K/AKT/GSK3β pathway activation and AD pathology improvement in mouse models
por: Pang, Shuo, et al.
Publicado: (2023)

Ginsenoside Rb3 Inhibits Pro-Inflammatory Cytokines via MAPK/AKT/NF-κB Pathways and Attenuates Rat Alveolar Bone Resorption in Response to Porphyromonas gingivalis LPS
por: Sun, Minmin, et al.
Publicado: (2020)

Stachydrine prevents LPS‐induced bone loss by inhibiting osteoclastogenesis via NF‐κB and Akt signalling
por: Meng, Jiahong, et al.
Publicado: (2019)

Neuroprotective Effects of Salidroside in the MPTP Mouse Model of Parkinson's Disease: Involvement of the PI3K/Akt/GSK3β Pathway
por: Zhang, Wei, et al.
Publicado: (2016)

Downregulation of BANCR Promotes Aggressiveness in Papillary Thyroid Cancer via the MAPK and PI3K Pathways: Erratum
por: Zhang, Jinjun, et al.
Publicado: (2023)

Retraction Note: Eupafolin induces apoptosis and autophagy of breast cancer cells through PI3K/AKT, MAPKs and NF-κB signaling pathways
por: Wei, Jiahui, et al.
Publicado: (2021)

Standardized ethanol extract of Tinospora crispa upregulates pro-inflammatory mediators release in LPS-primed U937 human macrophages through stimulation of MAPK, NF-κB and PI3K-Akt signaling networks
por: Haque, Md. Areeful, et al.
Publicado: (2020)

LPS-Primed Release of HMGB-1 from Cortical Astrocytes is Modulated Through PI3K/AKT Pathway
por: Xie, Ze-Feng, et al.
Publicado: (2015)

Baicalin Relieves LPS-Induced Lung Inflammation via the NF-κB and MAPK Pathways
por: Shen, Bingyu, et al.
Publicado: (2023)

Aerobic Exercise Regulates Apoptosis through the PI3K/Akt/GSK-3β Signaling Pathway to Improve Cognitive Impairment in Alzheimer's Disease Mice
por: Peng, Yan, et al.
Publicado: (2022)

Kaempferide Protects against Myocardial Ischemia/Reperfusion Injury through Activation of the PI3K/Akt/GSK-3β Pathway
por: Wang, Dong, et al.
Publicado: (2017)

Bergapten exerts inhibitory effects on diabetes-related osteoporosis via the regulation of the PI3K/AKT, JNK/MAPK and NF-κB signaling pathways in osteoprotegerin knockout mice
por: Li, Xue-Ju, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_cpkposocql70ujgiejc1r4q19n