In Vivo Tracking of Human Hematopoiesis Reveals Patterns of Clonal Dynamics during Early and Steady-State Reconstitution Phases

Hematopoietic stem/progenitor cells (HSPCs) are capable of supporting the lifelong production of blood cells exerting a wide spectrum of functions. Lentiviral vector HSPC gene therapy generates a human hematopoietic system stably marked at the clonal level by vector integration sites (ISs). Using IS...

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Detalles Bibliográficos
Autores principales: Biasco, Luca, Pellin, Danilo, Scala, Serena, Dionisio, Francesca, Basso-Ricci, Luca, Leonardelli, Lorena, Scaramuzza, Samantha, Baricordi, Cristina, Ferrua, Francesca, Cicalese, Maria Pia, Giannelli, Stefania, Neduva, Victor, Dow, David J., Schmidt, Manfred, Von Kalle, Christof, Roncarolo, Maria Grazia, Ciceri, Fabio, Vicard, Paola, Wit, Ernst, Di Serio, Clelia, Naldini, Luigi, Aiuti, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Short Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942697/
https://www.ncbi.nlm.nih.gov/pubmed/27237736
http://dx.doi.org/10.1016/j.stem.2016.04.016

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